Univariate analyses of clinical endpoints
| Variable | RR (95% CI) | p Value |
| Endpoint = recurrent ACS | ||
| BNP tercile 1 | 1.00 | |
| BNP tercile 2 | 1.54 (0.66 to 3.61) | 0.316 |
| BNP tercile 3 | 3.30 (1.53 to 7.11) | 0.002 |
| Log BNP (per pg/ml) | 2.20 (1.26 to 3.86) | 0.006 |
| GRACE tercile 1 | 1.00 | |
| GRACE tercile 2 | 2.13 (0.96 to 4.74) | 0.065 |
| GRACE tercile 3 | 2.38 (1.08 to 5.26) | 0.032 |
| GRACE (per point) | 1.009 (1.002 to 1.016) | 0.013 |
| Endpoint = CHF | ||
| BNP tercile 1 | 1.00 | |
| BNP tercile 2 | 2.44 (0.63 to 9.45) | 0.195 |
| BNP tercile 3 | 4.65 (1.31 to 16.48) | 0.017 |
| Log BNP (per pg/ml) | 4.32 (1.80 to 10.36) | 0.001 |
| GRACE tercile 1 | 1.00 | |
| GRACE tercile 2 | 2.79 (0.74 to 10.53) | 0.129 |
| GRACE tercile 3 | 3.96 (1.11 to 14.20) | 0.035 |
| GRACE (per point) | 1.016 (1.006 to 1.025) | 0.001 |
| End point = recurrent ACS/mortality | ||
| BNP tercile 1 | 1.00 | |
| BNP tercile 2 | 2.22 (1.00 to 4.90) | 0.049 |
| BNP tercile 3 | 5.51 (2.69 to 11.31) | <0.001 |
| Log BNP (per pg/ml) | 3.88 (2.40 to 6.27) | <0.001 |
| GRACE tercile 1 | 1.00 | |
| GRACE tercile 2 | 1.60 (0.84 to 3.07) | 0.156 |
| GRACE tercile 3 | 2.44 (1.33 to 4.49) | 0.004 |
| GRACE (per point) | 1.013 (1.008 to 1.019) | <0.001 |
| End point = CHF/mortality | ||
| BNP tercile 1 | 1.00 | |
| BNP tercile 2 | 2.53 (0.89 to 7.18) | 0.081 |
| BNP tercile 3 | 7.50 (2.92 to 19.26) | <0.001 |
| Log BNP (per pg/ml) | 6.23 (3.37 to 11.50) | <0.001 |
| GRACE tercile 1 | 1.00 | |
| GRACE tercile 2 | 3.15 (1.14 to 8.66) | 0.026 |
| GRACE tercile 3 | 6.30 (2.44 to 16.28) | <0.001 |
| GRACE (per point) | 1.02 (1.006 to 1.025) | <0.001 |
| End point = mortality | ||
| BNP tercile 1 | 1.00 | |
| BNP tercile 2 | 2.64 (0.51 to 13.63) | 0.245 |
| BNP tercile 3 | 14.10 (3.33 to 59.70) | <0.001 |
| Log BNP (per pg/ml) | 11.33 (4.93 to 26.04) | <0.001 |
| GRACE tercile 1 | 1.00 | |
| GRACE tercile 2 | 4.20 (0.89 to 19.78) | 0.070 |
| GRACE tercile 3 | 11.45 (2.68 to 48.83) | 0.001 |
| GRACE (per point) | 1.025 (1.018 to 1.032) | <0.001 |
| End points = all cardiovascular events (recurrent ACS/CHF or mortality) | ||
| BNP tercile 1 | 1.00 | |
| BNP tercile 2 | 2.28 (1.15 to 4.51) | 0.019 |
| BNP tercile 3 | 4.91 (2.62 to 9.22) | <0.001 |
| Log BNP (per pg/ml) | 3.57 (2.34 to 5.47) | <0.001 |
| GRACE tercile 1 | 1.00 | |
| GRACE tercile 2 | 1.74 (0.97 to 3.13) | 0.063 |
| GRACE tercile 3 | 2.51 (1.45 to 4.37) | 0.001 |
| GRACE (per point) | 1.013 (1.008 to 1.018) | <0.001 |
ACS, acute coronary syndrome; BNP, B-type natriuretic peptide; CHF, congestive heart failure; GRACE, Global Registry of Acute Coronary Events.