Discharge diagnosis | C-index (95% CI) | No of subjects | Linear predictor for 30-day mortality (L30) | |
STEMI (revised EMMACE model) | 0.80 (0.79 to 0.80) | 34 986 | −6.914+0.081× age+0.016×HR –0.016× SBP | |
NSTEMI | 0.76 (0.75 to 0.76) | 42 582 | −5.538+0.068×age+0.007×HR –0.018×SBP | |
Troponin-negative ACS | 0.77 (0.72 to 0.83) | 7369 | −13.340+0.099×age+0.020×HR –0.001× SBP | |
Chest pain of ? cause | 0.84 (0.77 to 0.92) | 3816 | −9.864+0.099×age+0.027×HR –0.016×SBP | |
Unconfirmed AMI | 0.73 (0.69 to 0.78) | 523 | −2.106+0.058×age+0.003×HR –0.015×SBP | |
Other diagnoses | 0.77 (0.75 to 0.78) | 7051 | −6.442+0.070×age+0.009×HR –0.014×SBP | |
All ACS patients | 0.78 (0.77 to 0.78) | 100 686 | −6.057+0.072×age+0.010×HR –0.017×SBP | |
Original EMMACE model (STEMI) | 0.76 (0.72 to 0.79) | 2153 | −5.624+0.085×age+0.014×HR –0.022×SBP |
STEMI, ST-elevation myocardial infarction with ECG evidence of ST-elevation consistence with infarction of ⩾2 mm in contiguous chest leads and or ST-elevation of ⩾1 mm in two or more standard leads, new left bundle branch block (LBBB) is also included. There is a creatinine kinase (CK) rise >2× upper limit of normal or troponin rise defined locally as that of an AMI. This group also contains threatened AMI as defined by rapid resolution of ST-elevation after reperfusion therapy associated with a CK rise <2× upper limit of normal or a small troponin rise.
NSTEMI, non-ST-elevation myocardial infarction with a history and ECG changes consistent with the diagnosis, and a CK rise >2× upper limit of normal or troponin rise defined locally as that of an AMI. This group also includes troponin-positive ACS as defined by symptoms consistent with cardiac ischaemia with release of troponin.
Troponin-negative ACS, symptoms consistent with cardiac ischaemia, and dynamic ECG changes with no release of troponin.
Chest pain of uncertain cause, any patient with chest pain not accompanied by significant ECG change or enzyme release and where no other clear diagnosis emerges.
Unconfirmed myocardial infarction, a history of chest pain of ECG changes, but where the patient dies before enzymes release or samples are taken.
Other diagnoses, any diagnosis other than cardiac ischaemia for patients admitted with suspected chest pain.