Independent predictors | Odds ratio (95% CI) | p Value |
PURSUIT | ||
Age* | 1.07 (1.07 to 1.08) | <0.001 |
Systolic blood pressure† | 0.98 (0.98 to 0.98) | <0.001 |
Heart rate‡ | 1.01 (1.01 to 1.01) | <0.001 |
Congestive cardiac failure | 1.54 (1.36 to 1.73) | <0.01 |
Raised cardiac markers | 2.65 (2.27 to 3.08) | <0.01 |
ST-segment depression | 1.27 (1.16 to 1.40) | <0.001 |
GUSTO-1 | ||
Systolic blood pressure† | 0.99 (0.99 to 1.00) | <0.001 |
Heart rate‡ | 1.01 (1.01 to 1.02) | <0.001 |
Congestive cardiac failure | 2.19 (1.65 to 2.9) | <0.001 |
Arrhythmia | 1.64 (1.17 to 2.29) | 0.004 |
History of stroke | 2.34 (1.90 to 2.89) | <0.001 |
History of hypertension | 1.13 (0.98 to 1.30) | 0.096 |
Age* | 1.09 (1.08 to 1.09) | <0.001 |
Long QRS duration | 1.72 (1.30 to 2.28) | <0.001 |
Smoker | 1.00 (0.84 to 1.20) | 0.972 |
GRACE in-hospital | ||
Age* | 1.08 (1.07 to 1.08) | <0.001 |
Congestive cardiac failure | 1.49 (1.32 to 1.62) | <0.001 |
Systolic blood pressure† | 0.98 (0.98 to 0.98) | <0.001 |
Raised cardiac markers | 2.11 (1.70 to 2.09) | <0.001 |
Chronic renal failure | 1.57 (1.32 to 1.75) | <0.001 |
ST-segment deviation | 1.46 (1.43 to 1.63) | <0.001 |
Heart rate‡ | 1.01 (1.01 to 1.01) | <0.001 |
GRACE 6-month | ||
Age* | 1.09 (1.08 to 1.09) | <0.001 |
Congestive cardiac failure | 1.75 (1.60 to 1.92) | <0.001 |
Systolic blood pressure† | 0.99 (0.99 to 0.99) | <0.001 |
Raised cardiac markers | 1.61 (1.47 to 1.75) | <0.001 |
Chronic renal failure | 2.01 (1.78 to 2.27) | <0.001 |
ST-segment deviation | 1.30 (1.22 to 1.37) | <0.001 |
Heart rate‡ | 1.01 (1.01 to 1.01) | <0.001 |
*Per 1-year increase; †per 1 mm Hg increase, ‡per 1-bpm increase.
EMMACE, Evaluation of the Methods and Management of Acute Coronary Events; GRACE, Global Registry of Acute Coronary Events; GUSTO-1, Global Utilisation of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries; PURSUIT, Predictors of Outcome in Patients with Acute Coronary Syndromes without Persistent ST Segment Elevation.