Table 1 Baseline characteristics
CharacteristicsIntact PTH (pg/ml)p Value
<47 pg/ml (n = 41)⩾47 pg/ml (n = 47)
Demographic and medical history
Age (years)69 (15)72 (14)0.31
Male sex, n (%)21 (51)14 (30)0.042
Hypertension, n (%)28 (68)41 (87)0.032
Diabetes mellitus, n (%)13 (32)11 (23)0.39
Atrial fibrillation, n (%)7 (17)13 (28)0.17
NYHA class III/IV, n (%)5 (12)25 (53)<0.001
Heart rate (bpm)76 (18)88 (26)0.010
Systolic blood pressure (mm Hg)133 (25)147 (30)0.022
Diastolic blood pressure (mm Hg)73 (15)83 (18)0.01
Aetiology of heart failure
Ischaemic heart disease, n (%)14 (34)17 (36)0.84
Diastolic heart failure, n (%)22 (54)19 (40)0.22
Dilated cardiomyopathy, n (%)1 (2)4 (9)0.22
Valvular heart disease, n (%)4 (10)7 (15)0.47
Drugs
ACE inhibitors/ARB, n (%)27 (66)29 (62)0.69
β Blockers, n (%)7 (17)10 (21)0.62
Calcium channel blockers, n (%)12 (29)20 (43)0.21
Diuretics, n (%)7 (17)15 (32)0.11
Laboratory measurements
B-type natriuretic peptide (pg/ml)226 (438)638 (914)0.012
Estimated GFR (ml/min/1.73 m2)74 (27)59 (24)0.009
Corrected calcium (mmol/l)2.33 (0.13)2.33 (0.13)0.79
Inorganic phosphate (mmol/l)1.13 (0.19)1.13 (0.26)0.83
Magnesium (mmol/l)0.91 (0.16)0.82 (0.08)0.18
Haemoglobin (g/l)129 (23)120 (26)0.12
Haemoglobin A1c0.061 (0.014)0.059 (0.009)0.49
Echocardiography
LA diameter (mm)42 (9)44 (10)0.51
LV end-diastolic diameter (mm)53 (9)54 (8)0.49
LV end-systolic diameter (mm)35 (10)39 (11)0.085
LV fractional shortening (%)35 (10)30 (10)0.019
LV ejection fraction (%)63 (13)54 (16)0.012
  • Values are given as mean (SD) unless stated otherwise.

  • ACE, angiotensin converting enzyme; ARB, angiotensin receptor blockers; GFR, glomerular filtration rate; LV, left ventricular; NYHA, New York Heart Association; PTH, parathyroid hormone.