Characteristics | Intact PTH (pg/ml) | p Value | |
<47 pg/ml (n = 41) | ⩾47 pg/ml (n = 47) | ||
Demographic and medical history | |||
Age (years) | 69 (15) | 72 (14) | 0.31 |
Male sex, n (%) | 21 (51) | 14 (30) | 0.042 |
Hypertension, n (%) | 28 (68) | 41 (87) | 0.032 |
Diabetes mellitus, n (%) | 13 (32) | 11 (23) | 0.39 |
Atrial fibrillation, n (%) | 7 (17) | 13 (28) | 0.17 |
NYHA class III/IV, n (%) | 5 (12) | 25 (53) | <0.001 |
Heart rate (bpm) | 76 (18) | 88 (26) | 0.010 |
Systolic blood pressure (mm Hg) | 133 (25) | 147 (30) | 0.022 |
Diastolic blood pressure (mm Hg) | 73 (15) | 83 (18) | 0.01 |
Aetiology of heart failure | |||
Ischaemic heart disease, n (%) | 14 (34) | 17 (36) | 0.84 |
Diastolic heart failure, n (%) | 22 (54) | 19 (40) | 0.22 |
Dilated cardiomyopathy, n (%) | 1 (2) | 4 (9) | 0.22 |
Valvular heart disease, n (%) | 4 (10) | 7 (15) | 0.47 |
Drugs | |||
ACE inhibitors/ARB, n (%) | 27 (66) | 29 (62) | 0.69 |
β Blockers, n (%) | 7 (17) | 10 (21) | 0.62 |
Calcium channel blockers, n (%) | 12 (29) | 20 (43) | 0.21 |
Diuretics, n (%) | 7 (17) | 15 (32) | 0.11 |
Laboratory measurements | |||
B-type natriuretic peptide (pg/ml) | 226 (438) | 638 (914) | 0.012 |
Estimated GFR (ml/min/1.73 m2) | 74 (27) | 59 (24) | 0.009 |
Corrected calcium (mmol/l) | 2.33 (0.13) | 2.33 (0.13) | 0.79 |
Inorganic phosphate (mmol/l) | 1.13 (0.19) | 1.13 (0.26) | 0.83 |
Magnesium (mmol/l) | 0.91 (0.16) | 0.82 (0.08) | 0.18 |
Haemoglobin (g/l) | 129 (23) | 120 (26) | 0.12 |
Haemoglobin A1c | 0.061 (0.014) | 0.059 (0.009) | 0.49 |
Echocardiography | |||
LA diameter (mm) | 42 (9) | 44 (10) | 0.51 |
LV end-diastolic diameter (mm) | 53 (9) | 54 (8) | 0.49 |
LV end-systolic diameter (mm) | 35 (10) | 39 (11) | 0.085 |
LV fractional shortening (%) | 35 (10) | 30 (10) | 0.019 |
LV ejection fraction (%) | 63 (13) | 54 (16) | 0.012 |
Values are given as mean (SD) unless stated otherwise.
ACE, angiotensin converting enzyme; ARB, angiotensin receptor blockers; GFR, glomerular filtration rate; LV, left ventricular; NYHA, New York Heart Association; PTH, parathyroid hormone.