Table 3

LA function and filling pressure

HFNEF (n=50)Hypertension (n=15)Healthy controls (n=30)p-Value for one way ANOVA
A rest, m/s0.86 (0.18)* 0.73 (0.17)0.69 (0.12)<0.001
A Ex, m/s1.01 (0.18)*0.95 (0.22)0.91 (0.17)0.049
Δ A, m/s0.16 (0.13)0.22 (0.16)0.22 (0.13)0.132
E/E′ rest11.9 (4.5)* 8.1 (1.5)8.4 (1.8)<0.001
E/E′ Ex10.9 (3.3)*10.1 (2.6)8.3 (1.6)0.035
Am rest, cm/s7.2 (1.5)6.7 (2.3)7.9 (1.6)0.057
Am Ex, cm/s8.2 (1.7)* 9.6 (2.6)10.0 (2.2)0.001
ΔAm, cm/s1.0 (1.6)* 2.9 (1.5)2.1 (1.6)<0.001
Atrial FRI0.84 (1.34)* 2.39 (1.27)1.81 (1.39)<0.001
  • A, late mitral diastolic inflow velocity; Am, late diastolic annular velocity; atrial FRI, atrial functional reserve index; E/E′, ratio of early mitral diastolic inflow velocity to early diastolic mitral annular velocity; Ex, on exercise.

  • Data are mean (SD).

  • Tukey post hoc analysis:

  • * p<0.05 compared with healthy controls.

  • p<0.05 compared with hypertensive group.