1987–1991 | 1992–1996 | 1997–2001 | 2002–2006 | ||
Unexplained chest pain | |||||
Number | 34 410 | 49 834 | 73 829 | 77 782 | |
Age, mean (SD), yr | 58.0 (14.2) | 57.8 (14.4) | 57.6 (14.1) | 58.5 (13.7) | <0.0001 |
Women, % | 14 487 (42.1) | 23 621 (47.4) | 35 659 (48.3) | 39 513 (50.8) | <0.0001 |
Length of stay, mean (SD), d | 2.4 (2.6) | 1.7 (1.9) | 1.5 (1.5) | 1.3 (1.4) | <0.0001 |
Length of stay, median (IQR), d | 2.0 (1.0–3.0) | 1.0 (1.0–2.0) | 1.0 (1.0–1.0) | 1.0 (1.0–1.0) | |
Coronary angiography within 30 d, n (%) | – | – | 1189 (1.6) | 3533 (4.5) | <0.0001 |
PCI within 30 d, n (%) | – | – | 189 (0.3) | 582 (0.7) | <0.0001 |
CABG within 30 d, n (%) | – | – | 75 (0.1) | 139 (0.2) | 0.0002 |
Diabetes, % | 1010 (2.9) | 1644 (3.3) | 2555 (3.5) | 3758 (4.8) | <0.0001 |
Hypertension, % | 2010 (5.8) | 3760 (7.5) | 6973 (9.4) | 11 937 (15.3) | <0.0001 |
Prior stroke, % | 1167 (3.4) | 1849 (3.7) | 2448 (3.3) | 2313 (3.0) | <0.0001 |
Valvular disease, % | 374 (1.1) | 577 (1.2) | 781 (1.1) | 916 (1.2) | 0.22 |
Atrial fibrillation, % | 1131 (3.3) | 2182 (4.4) | 3169 (4.3) | 3599 (4.6) | <0.0001 |
Cardiomyopathy, % | 60 (0.2) | 127 (0.3) | 257 (0.3) | 300 (0.4) | <0.0001 |
Pulmonary embolism, % | 416 (1.2) | 565 (1.1) | 765 (1.0) | 696 (0.9) | <0.0001 |
Any other circulatory diagnosis, % | 1920 (5.6) | 2244 (4.5) | 2699 (3.7) | 2198 (2.8) | <0.0001 |
Chronic obstructive lung disease, % | 652 (0.9) | 1254 (2.5) | 1070 (1.4) | 1171 (1.5) | <0.0001 |
Asthma, % | 345 (0.4) | 688 (1.4) | 899 (1.2) | 1128 (1.5) | <0.0001 |
Malignant disease, % | 2227 (6.3 | 3034 (6.1) | 4190 (5.7) | 4105 (5.3) | <0.0001 |
Angina | |||||
Number | 32 913 | 38 474 | 41 452 | 29 760 | |
Age, mean (SD), yr | 67.6 (10.4) | 67.5 (10.8) | 67.4 (10.9) | 67.1 (10.8) | <0.0001 |
Women, % | 13 494 (41.0) | 16 582 (43.1) | 18 032 (43.5) | 11 993 (40.3) | <0.0001 |
Length of stay, mean (SD), d | 4.3 (4.3) | 3.7 (3.6) | 3.6 (3.6) | 3.5 (4.3) | <0.0001 |
Length of stay, median (IQR), d | 3.0 (2.0–5.0) | 3.0 (1.0–5.0) | 3.0 (1.0–5.0) | 2.0 (1.0–4.0) | |
Coronary angiography within 30 d, n (%) | – | – | 8440 (20.4) | 12 546 (42.2) | <0.0001 |
PCI within 30 d, n (%) | – | – | 3873 (9.3) | 7156 (24.1) | <0.0001 |
CABG within 30 d, n (%) | – | – | 2989 (7.2) | 3293 (11.1) | <0.0001 |
Diabetes, % | 2135 (6.5) | 3040 (7.9) | 3595 (8.7) | 3160 (10.6) | <0.0001 |
Hypertension, % | 3294 (10.0) | 5322 (13.8) | 6738 (16.3) | 7307 (24.6) | <0.0001 |
Prior stroke, % | 1966 (6.0) | 2285 (5.9) | 2440 (5.9) | 1413 (4.8) | <0.0001 |
Valvular disease, % | 775 (2.4) | 1012 (2.6) | 906 (2.2) | 737 (2.5) | 0.19 |
Atrial fibrillation, % | 1849 (5.6) | 2825 (7.3) | 2995 (7.2) | 2171 (7.3) | <0.0001 |
Cardiomyopathy, % | 99 (0.3) | 159 (0.4) | 177 (0.4) | 130 (0.4) | <0.0001 |
Pulmonary embolism, % | 262 (0.8) | 295 (0.8) | 269 (0.6) | 182 (0.6) | 0.002 |
Any other circulatory diagnosis, % | 2207 (6.7) | 2219 (5.8) | 2137 (5.2) | 1244 (4.2) | <0.0001 |
Chronic obstructive lung disease, % | 872 (2.6) | 1315 (3.4) | 921 (2.2) | 695 (2.3) | <0.0001 |
Asthma, % | 434 (1.3) | 663 (1.7) | 659 (1.6) | 411 (1.4) | 0.08 |
Malignant disease, % | 2145 (6.5) | 2444 (6.4) | 2503 (6.0) | 1649 (5.6) | <0.0001 |
PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; IQR, interquartile range.