Table 2

Adjusted HRs (95% CI) for moderate to severe myopathy. Models also adjusted for age and body mass index

Women adjusted HR (95% CI)Men adjusted HR (95% CI)
Non-users of statins1.001.00
New users of statins2.97 (2.36 to 3.74)6.15 (5.19 to 7.30)
Ethnicity
White or not recorded1.001.00
Indian1.42 (0.63 to 3.19)1.96 (1.15 to 3.34)
Pakistani1.41 (0.45 to 4.41)1.68 (0.80 to 3.55)
Bangladeshi*NA0.61 (0.09 to 4.32)
Other Asian*NA0.48 (0.07 to 3.44)
Caribbean3.94 (2.34 to 6.64)6.57 (4.55 to 9.48)
Black African4.47 (2.21 to 9.04)7.87 (5.30 to 11.68)
Chinese1.44 (0.20 to 10.28)2.10 (0.52 to 8.40)
Other ethnic group2.54 (1.31 to 4.92)2.84 (1.78 to 4.53)
Comorbidity
Type 1 diabetes4.78 (2.10 to 10.86)NS
Type 2 diabetes1.84 (1.39 to 2.43)1.38 (1.12 to 1.69)
Treated hypertension1.62 (1.31 to 2.01)NS
Chronic liver disease3.47 (1.55 to 7.78)NS
Hypothyroidism1.88 (1.42 to 2.50)NS
Corticosteroids3.03 (2.38 to 3.85)2.09 (1.60 to 2.72)
  • Fractional polynomial terms

    women: age3, age3 ln(age), men: age3, age3 ln(age), bmi not significant in women, linear in men.

  • * Insufficient data in women.