Table 5

Adjusted HR (95% CI) for moderate/serious liver dysfunction. Models also adjusted for age and body mass index

Women adjusted HR (95% CI)Men adjusted HR (95% CI)
Non-users of statins1.001.00
New users of statins1.53 (1.41 to 1.66)1.53 (1.42 to 1.66)
Townsend score (5 unit increase)0.93 (0.98 to 0.99)1.02 (1.00 to 1.01)
Ethnicity
White or not recorded1.001.00
Indian0.94 (0.7 to 1.26)1.16 (0.90 to 1.50)
Pakistani1.45 (1.05 to 2.00)1.18 (0.85 to 1.63)
Bangladeshi1.41 (0.8 to 2.50)1.31 (0.81 to 2.11)
Other Asian1.62 (1.1 to 2.39)1.43 (0.96 to 2.13)
Caribbean0.51 (0.34 to 0.76)0.86 (0.62 to 1.20)
Black African0.74 (0.49 to 1.12)0.56 (0.36 to 0.87)
Chinese1.40 (0.81 to 2.42)1.29 (0.73 to 2.28)
Other ethnic group0.94 (0.72 to 1.24)1.17 (0.93 to 1.49)
Smoking status
Non-smoker1.001.00
Ex-smoker1.06 (1.00 to 1.13)1.14 (1.08 to 1.21)
Light smoker1.12 (1.01 to 1.24)1.21 (1.12 to 1.32)
Moderate smoker1.23 (1.13 to 1.34)1.19 (1.09 to 1.29)
Heavy smoker1.36 (1.23 to 1.51)1.34 (1.23 to 1.45)
Comorbidity
Type 1 diabetes2.15 (1.51 to 3.07)1.52 (1.09 to 2.13)
Type 2 diabetes1.13 (1.00 to 1.27)1.45 (1.31 to 1.60)
Cardiovascular disease1.14 (1.02 to 1.27)1.22 (1.11 to 1.34)
Treated hypertension1.23 (1.15 to 1.32)1.40 (1.31 to 1.51)
Rheumatoid arthritis2.42 (2.13 to 2.76)1.90 (1.53 to 2.36)
Corticosteroids1.47 (1.34 to 1.61)1.44 (1.29 to 1.62)
  • Fractional polynomial terms

    women; age2, age2 ln(age), bmi3, bmi3ln(bmi), men age−2, age3, bmi−2, bmi−2 ln(bmi).