Demographic profile of subjects
| Normal (n = 32) | HbA1C <8 (n = 31) | HbA1C ⩾8 (n = 38) | |
| Age (years) | 48.8 (5.3) | 50.6 (7.3) | 50.3 (4.6) |
| BMI (kg/m2)‡ | 23.81* (3.4) | 26.42 (2.8) | 26.57 (3.8) |
| Systolic blood pressure (mm Hg) | 116 (10) | 120 (12) | 117 (11) |
| Diastolic blood pressure (mm Hg) | 80 (9) | 80 (7) | 78 (9) |
| Cardiac output (l/ml) | 4.96 (0.95) | 5.10 (0.91) | 5.19 (0.76) |
| Heart rate | 77 (11) | 80 (14) | 80 (10) |
| NT-proBNP (pg/ml)† | 31 (14.5–51.5) | 35.1 (11.5–62.7) | 27.6 (14.6–55.7) |
| VCAM (ng/ml)† | 326.8 (186–647) | 343.8 (171–617) | 416.9 (253–611) |
| Diabetes duration (years)† | – | 4 (3–10) | 5 (3–10) |
| Microalbuminuria (mg/l) | 18.99 (44.93) | 17.85 (36.35) | 41.05 (88.11) |
| eGFR (ml/min/1.73 m2) | 85 (12) | 80 (16) | 90 (17) |
| Concomitant medication | |||
| Secretagogues | – | 70 | 73 |
| Sensitisers | – | 73 | 76 |
| β-blockers‡ | – | 33 | 5** |
| Antihypertensives | – | 50 | 34 |
| Diuretics | – | 7 | 3 |
| Statins | – | 8.3 | 0 |
Values are means (SD) or †median (interquartile range).
*p<0.01 normal vs <8, normal vs ⩾8; **p<0.05 <8 vs ⩾8.
‡Does not alter and contribute to diabetic vs non-diabetic comparison for various ICG and O2C variables.