Random effects meta–regression analysis of studies examining the effect of smoke-free legislation on acute coronary events
| Univariate | Multivariate | |||||
| Coefficient (95% CI) | p Value | Multiplicity adjusted p value | Coefficient (95% CI) | p Value | Multiplicity adjusted p value | |
| Study population size | ||||||
| ≥500 000 | – | – | – | – | – | |
| <500 000 | 0.050 (−0.044 to 0.145) | 0.294 | 0.314 | 0.029 (−0.075 to 0.134) | 0.584 | 0.967 |
| Age category | ||||||
| Old age | – | – | ||||
| Young | −0.005 (−0.106 to 0.0096) | 0.925 | 0.998 | −0.023 (−0.111 to 0.065) | 0.601 | 0.953 |
| All age | −0.138 (−0.236 to −0.040) | 0.006 | 0.035 | −0.023 (−0.148 to 0.103) | 0.720 | 0.990 |
| Study location | ||||||
| America | – | – | – | |||
| Europe | 0.198 (0.098 to 0.300) | <0.001 | 0.014 | 0.061 (−0.084 to 0.207) | 0.406 | 0.938 |
| Australasia | 0.230 (0.089 to 0.370) | 0.001 | 0.027 | 0.190 (0.020 to 0.360) | 0.029 | 0.239 |
| Months of follow-up after legislation | −0.005 (−0.007 to −0.002) | <0.001 | 0.001 | −0.005 (−0.007 to −0.002) | <0.001 | 0.006 |
| Year of publication | 0.044 (−0.001 to 0.089) | 0.058 | 0.097 | 0.051 (0.009 to 0.092) | 0.016 | 0.131 |
Adjusted R2=57.82%.
I2 (res)=72.63%.
τ2=0.0057.