Age at recruitment (years), mean (SD) | 50.42 | (7.32) | 51.84 | (7.57) | 50.51 | (7.38) | 50.5 | (7.28) | 50.84 | (7.07) | 51.29 | (6.84) | 0.800 |
Height (cm), mean (SD) | 168.62 | (6.22) | 168.30 | (6.53) | 168.74 | (6.54) | 169.12 | (6.47) | 169.06 | (6.13) | 169.47 | (6.02) | <0.001 |
Weight (kg), mean (SD) | 80.22 | (11.16) | 81.04 | (11.26) | 80.44 | (11.16) | 80.95 | (10.63) | 81.50 | (10.43) | 84.11 | (11.72) | <0.001 |
Waist/hip ratio, mean (SD) | 0.93 | (0.05) | 0.94 | (0.05) | 0.94 | (0.06) | 0.94 | (0.059 | 0.94 | (0.05) | 0.95 | (0.05) | <0.001 |
Energy intake (kcal/day), mean (SD) | 2302.56 | (667.74) | 2310.28 | (654.23) | 2448.83 | (679.03) | 2564.30 | (658.84) | 2888.02 | (652.55) | 3561.84 | (823.30) | <0.001 |
Tobacco status (%) | | | | | | | | | | | | | |
Never-smoker | 47.0 | | 26.5 | | 36.6 | | 30.9 | | 25.2 | | 17.8 | | <0.001 |
Former smoker | 25.6 | | 38.4 | | 31.6 | | 31.5 | | 28.9 | | 25.4 | | |
Smoker | 27.4 | | 35.1 | | 31.8 | | 37.6 | | 45.8 | | 56.8 | | |
Total physical activity index (%) | | | | | | | | | | | | | |
Inactive | 21.5 | | 22.0 | | 24.1 | | 22.4 | | 20.1 | | 17.8 | | <0.001 |
Moderately inactive | 31.1 | | 29.5 | | 31.1 | | 30.3 | | 28.6 | | 29.8 | | |
Moderately active | 32.2 | | 32.3 | | 30.5 | | 32.7 | | 36.4 | | 36.4 | | |
Active | 15.3 | | 16.2 | | 14.3 | | 14.5 | | 15.0 | | 16.0 | | |
Body mass index (kg/m2) (%) | | | | | | | | | | | | | |
Underweight | 0.3 | | 0.4 | | 0.4 | | 0.3 | | 0.2 | | 0.3 | | <0.001 |
Normal weight | 16.4 | | 13.0 | | 14.3 | | 14.6 | | 12.2 | | 10.0 | | |
Overweight | 57.5 | | 54.6 | | 59.3 | | 57.7 | | 58.1 | | 50.5 | | |
Obese | 25.8 | | 32.0 | | 26.0 | | 27.4 | | 29.5 | | 39.2 | | |
Educational level (%) | | | | | | | | | | | | | |
None | 20.0 | | 26.3 | | 24.5 | | 23.0 | | 25.6 | | 28.1 | | <0.001 |
Primary | 33.3 | | 44.1 | | 33.9 | | 36.5 | | 40.3 | | 46.9 | | |
Technical | 13.0 | | 12.1 | | 11.8 | | 12.9 | | 14.4 | | 12.4 | | |
Secondary | 11.3 | | 6.6 | | 8.9 | | 8.7 | | 8.1 | | 5.5 | | |
University degree | 22.5 | | 11.0 | | 20.9 | | 18.8 | | 11.5 | | 7.1 | | |
Diabetes (%) | | | | | | | | | | | | | |
Yes | 5.7 | | 9.9 | | 5.9 | | 5.4 | | 5.2 | | 6.1 | | <0.001 |
High blood pressure (%) | | | | | | | | | | | | | |
Yes | 18.8 | | 27.7 | | 21.8 | | 20.0 | | 20.9 | | 23.6 | | 0.103 |
Hyperlipidaemia (%) | | | | | | | | | | | | | |
Yes | 19.5 | | 27.1 | | 24.1 | | 25.6 | | 28.0 | | 29.9 | | <0.001 |
Vitamin E (mg/day), mean (SD) | 10.6 | (6.1) | 11.3 | (7.3) | 11.6 | (6.9) | 11.9 | (7.2) | 12.4 | (7.5) | 12.0 | (8.7) | <0.001 |
B01/B02 (antithrombotic and antihaemorrhagic) (%) | | | | | | | | | | | | | |
Yes | 1.1 | | 2.7 | | 1.1 | | 0.8 | | 0.6 | | 0.4 | | <0.001 |
C01–C10 (cardiovascular), (%) | | | | | | | | | | | | | |
Yes | 10.7 | | 15.3 | | 12.8 | | 10.1 | | 9.3 | | 9.4 | | <0.001 |
N02BA (aspirin), (%) | | | | | | | | | | | | | |
Yes | 4.5 | | 3.5 | | 3.3 | | 4.2 | | 3.7 | | 4.4 | | 0.771 |