Table 3

Results of subgroup analyses and covariate analysis

CovariateNumber of studiesSensitivity (95% CI)Specificity (95% CI)
Point-of-care test
 Yes80.81 (0.69 to 0.90)0.85 (0.74 to 0.92)
 No80.86 (0.75 to 0.93)0.84 (0.73 to 0.91)
 p Value0.470.89
Reference standard with troponin
 Yes100.76 (0.67 to 0.84)0.88 (0.81 to 0.93)
 No60.91 (0.84 to 0.95)0.78 (0.64 to 0.88)
 p Value0.0040.11
Impact of prevalence of outcome
 20%All0.82 (0.65 to 0.92)0.90 (0.82 to 0.95)
 40%0.84 (0.76 to 0.90)0.84 (0.77 to 0.89)
 p Value0.710.046
Impact of cut-off value
 5All0.85 (0.73 to 0.92)0.80 (0.69 to 0.88)
 70.84 (0.76 to 0.90)0.83 (0.76 to 0.89)
 140.82 (0.58 to 0.94)0.91 (0.78 to 0.97)
 p Value0.820.20