Baseline characteristics
| No coronary heart disease during follow-up (n=20089) | Coronary heart disease during follow-up (n=2752) | |||||
| Negative | Positive | p Value | Negative | Positive | p Value | |
| n=14866 | n=5223 | n=1907 | n=845 | |||
| Age (years) | 57±9 | 59±9 | <0.001 | 65±8 | 65±7 | 0.03 |
| Male sex | 42.1 (6257) | 42.4 (2217) | 0.65 | 66.6 (1271) | 64.3 (543) | 0.22 |
| Body mass index (kg/m2) | 26.1±3.8 | 26.2±3.8 | 0.40 | 27.1±3.9 | 27.0±3.8 | 0.40 |
| Waist circumference (cm) | 87±12 | 87±12 | 0.33 | 94±12 | 93±11 | 0.16 |
| Waist/hip ratio | 0.85±0.09 | 0.85±0.09 | 0.36 | 0.90±0.09 | 0.90±0.08 | 0.33 |
| Current smoking | 11.7 (1735) | 10.2 (535) | 0.02 | 13.7 (261) | 12.3 (104) | 0.5 |
| Diabetes mellitus | 1.4 (211) | 1.6 (83) | 0.38 | 6.2 (119) | 6.0 (51) | 0.84 |
| Systolic blood pressure (mm Hg) | 134±18 | 136±18 | <0.001 | 142±19 | 141±19 | 0.18 |
| Diastolic blood pressure, (mm Hg) | 82±11 | 83±11 | <0.001 | 85±12 | 84±12 | 0.02 |
| Total cholesterol (mmol/l) | 6.1±1.1 | 6.2±1.1 | <0.001 | 6.4±1.2 | 6.4±1.1 | 0.82 |
| Low-density lipoprotein cholesterol (mmol/l) | 3.9±1.0 | 4.0±1.0 | <0.001 | 4.2±1.0 | 4.2±1.0 | 0.62 |
| High-density lipoprotein cholesterol (mmol/l) | 1.4±0.4 | 1.4±0.4 | 0.60 | 1.3±0.4 | 1.3±0.4 | 0.80 |
| Triglycerides (mmol/l) | 1.5 (1.0 to 2.1) | 1.5 (1.1 to 2.1) | <0.001 | 1.8 (1.3 to 2.5) | 1.8 (1.3 to 2.5) | 0.20 |
| Framingham Risk Score | 17.1 (3.0 to 23.8) | 18.6 (4.3 to 26.4) | <0.001 | 31.8 (16.4 to 42.1) | 33.0 (16.2 to 44.3) | 0.19 |
Data are presented as a percentage (number), mean±SD or median (IQR).