RR for future coronary heart disease according to status of coronary heart disease
| Family history | |||
| None | Premature | Non-premature | |
| Any first-degree relative | |||
| Cases/total | 1526/14585 | 381/2188 | 845/6068 |
| Unadjusted | 1 | 1.74 (1.55 to 1.95) | 1.36 (1.25 to 1.48) |
| Adjusted for sex and age | 1 | 1.91 (1.71 to 2.14) | 1.29 (1.18 to 1.40) |
| Adjusted for Framingham Risk Score | 1 | 1.74 (1.56 to 1.95) | 1.30 (1.20 to 1.41) |
| Parental history | |||
| Cases/total | 1995/16691 | 165/1146 | 592/5004 |
| Unadjusted | 1 | 1.22 (1.04 to 1.43) | 0.99 (0.90 to 1.09) |
| Adjusted for sex and age | 1 | 1.61 (1.38 to 1.89) | 1.10 (1.01 to 1.21) |
| Adjusted for Framingham Risk Score | 1 | 1.43 (1.22 to 1.68) | 1.05 (0.96 to 1.15) |
| Sibling history | |||
| Cases/total | 2515/21681 | 87/490 | 150/670 |
| Unadjusted | 1 | 1.58 (1.27 to 1.95) | 2.04 (1.73 to 2.40) |
| Adjusted for sex and age | 1 | 1.44 (1.17 to 1.79) | 1.18 (1.00 to 1.40) |
| Adjusted for Framingham Risk Score | 1 | 1.43 (1.15 to 1.77) | 1.47 (1.25 to 1.74) |
Premature is defined as <55 years in men and <65 years in women. Non-premature is defined as ≥55 years in men and ≥65 in women.