Baseline variables for the group study
| Patients | Controls | |
| Heart rate (bpm) | 82 (15) | 67 (8)* |
| Systolic blood pressure (mm Hg) | 120 (20) | 116 (10) |
| Diastolic blood pressure (mm Hg) | 80 (10) | 75 (7) |
| 6MWD (m) | 361 (103) | – |
| NYHA functional class | – | |
| 2 | 6 | – |
| 3 | 10 | – |
| Standard echocardiography | ||
| RV end-diastolic area (cm2) | 27.4 (6.3) | 13 (2)* |
| RV end-systolic area (cm2) | 19.6 (5) | 6 (1)* |
| RV fractional area change (%) | 29.4 (5.7) | 54 (5)* |
| TAPSE (mm) | 14.5 (4.4) | 24 (6)* |
| RV-RA pressure gradient (mm Hg) | 75 (12.5) | 20 (5)* |
| Systolic PAP (mm Hg) | 86 (12) | 24 (6)* |
| LV ejection fraction (%) | 62 (7) | 65 (7.5) |
| Myocardial deformation imaging | ||
| Peak S ejection basal segment (%) | −12.2 (4.6) | −26.4 (5.6)* |
| Peak S ejection mid-apical segment (%) | −8.8 (4.6) | −26.2 (8.2)* |
| Peak SR ejection basal segment (s−1) | −0.77 (0.27) | −1.76 (0.6)* |
| Peak SR ejection mid-apical segment (s−1) | −0.76 (0.34) | −1.57 (0.5)* |
| Heart catheterisation | ||
| Systolic PAP (mm Hg) | 75 (71–81) | – |
| Diastolic PAP (mm Hg) | 26 (22–34) | – |
| Mean PAP (mm Hg) | 43 (38–51) | – |
| PVR (dyne*s/cm5) | 902 (662–1283) | – |
| CI (l/min*m2) | 1.6 (1.3–1.8) | – |
↵* p<0.001 controls versus CTEPH patients.
6MWD, 6-minute walking distance; CI, indexed cardiac output; CTEPH, chronic thromboembolic pulmonary hypertension; LV, left ventricular; PAP, pulmonary arterial pressure; PVR, pulmonary vascular resistance; RA, right auricle; RV, right ventricle; SR, strain rate, TAPSE, tricuspid annular plane systolic excursion.