Childhood adversity | Men | Women | ||||
n (no of cases) | Model 1* | Model 2† | n (no of cases) | Model 1* | Model 2† | |
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |||
Parental divorce | ||||||
No | 7852 (134) | 1.00 | 1.00 | 11322 (80) | 1.00 | 1.00 |
Yes | 1531 (32) | 1.59 (1.06 to 2.37) | 0.95 (0.63 to 1.43) | 2490 (14) | 1.08 (0.61 to 1.93) | 0.75 (0.42 to 1.33) |
Financial difficulties | ||||||
No | 6417 (104) | 1.00 | 1.00 | 8914 (55) | 1.00 | 1.00 |
Yes | 2212 (56) | 1.20 (0.89 to 1.63) | 1.10 (0.78 to 1.55) | 3591 (29) | 1.06 (0.67 to 1.68) | 1.02 (0.64 to 1.64) |
Interpersonal conflicts | ||||||
No | 6590 (106) | 1.00 | 1.00 | 8881 (56) | 1.00 | 1.00 |
Yes | 2057 (49) | 1.53 (1.09 to 2.15) | 1.14 (0.80 to 1.63) | 3808 (34) | 1.52 (0.99 to 2.33) | 1.23 (0.79 to 1.93) |
Fear of a family member | ||||||
No | 8310 (139) | 1.00 | 1.00 | 11379 (65) | 1.00 | 1.00 |
Yes | 903 (26) | 1.53 (1.00 to 2.34) | 1.26 (0.81 to 1.96) | 2123 (26) | 2.02 (1.28 to 3.19) | 1.65 (1.01 to 2.67) |
Longstanding illness | ||||||
No | 7116 (105) | 1.00 | 1.00 | 10176 (62) | 1.00 | 1.00 |
Yes | 2306 (69) | 1.64 (1.20 to 2.23) | 1.91 (1.40 to 2.61) | 3687 (35) | 1.15 (0.75 to 1.75) | 1.31 (0.86 to 2.01) |
Alcohol-related problems | ||||||
No | 7288 (111) | 1.00 | 1.00 | 10001 (73) | 1.00 | 1.00 |
Yes | 2030 (59) | 2.01 (1.46 to 2.77) | 1.51 (1.08 to 2.11) | 3674 (22) | 0.87 (0.54 to 1.40) | 0.75 (0.46 to 1.22) |
↵* Model 1 adjusted for age group (20–24, 30–34, 40–44 and 50–54 years) at baseline.
↵† Model 2 additionally adjusted for education (basic, secondary, lower tertiary, higher tertiary education), current smoking (yes or no), high alcohol intake (<200 g/≥200 g of pure alcohol per week), body mass index (<30/≥30 kg/m2), physical activity (<2/≥2 metabolic equivalent task hours/day), depression (a sum score of ≤18/>18 in the Beck Depression Inventory) and medical conditions (hypertension or diabetes, derived from the National Drug Reimbursement Register or from the National Hospital Discharge Register).