Table 2

Hospital care and follow-up

WomenMenp Value
(n=384)(n=1748)
Symptom-to-door time (h:m) median
(IQR)
1:52
(1.00–4:42)
1:45
(1:00–3:49)
0.18
Treatment in coronary care unit
 Acute reperfusion therapy*78.1 (300)80.5 (1408)0.28
Fibirinolytic therapy44.6 (171)48.4 (837)0.19
Primary percutaneous coronary intervention41.4 (159)41.5 (725)0.98
Acute coronary artery bypass surgery0.03 (1)0.03 (6)0.79
IV β-blockers51.3 (195)54.6 (938)0.25
IV nitrates33.8 (127)36.7 (623)0.28
Cardiac procedures
Coronary angiography within 1 days after admission45.6 (175)45.4 (793)0.94
Coronary angiography within 7 days after admission59.6 (229)58.8 (1028)0.77
Echocardiography/other LV-function assessment†73.1 (274)73.7 (1251)0.81
Complications
 Killip class on admission
Class I87.6 (318)90.6 (1488)0.25
Class II5.0 (18)5.2 (85)0.89
Class III1.1 (4)0.7 (12)0.47
Class IV6.3 (23)3.5 (57)0.01
 Left ventricular ejection fraction ≥50%49.0 (77)55.0 (360)0.18
 Signs of heart failure during hospital care‡19.4 (74)15.4 (266)0.06
 Second-degree to third-degree atrioventricular block3.0 (12)2.2 (39)0.34
 Bleeding§2.2 (5)1.0 (11)0.16
 Resuscitation before hospital care2.1 (8)1.2 (21)0.18
 Resuscitation during hospital care5.0 (19)4.8 (82)0.85
 Re-infarction during hospital care2.4 (9)1.2 (20)0.07
 In-hospital mortality2.9 (11)1.0 (18)0.005
Prescriptions at discharge in hospital survivors(n=373)(n=1725)
 Aspirin/other platelet inhibitors94.6 (350)94.0 (1594)0.68
 Oral anticoagulants7.9 (29)7.8 (131)0.97
 β-Blockers87.3 (322)90.9 (1542)0.03
ACE inhibitors/angiotensin receptor II blockers38.6 (142)41.7 (700)0.27
 Statins/other lipid-lowering drugs61.5 (225)70.9 (1194)<0.001
 Calcium-channel blockers8.2 (30)4.6 (76)0.005
 Diuretics9.6 (35)7.8 (130)0.26
 Long-acting nitrates13.7 (50)11.1 (185)0.16
Mortality and re-infarctions at follow-up
 One year mortality3.7 (14)2.2 (39)0.01
 Long-term mortality¶7.0 (27)6.2 (108)0.54
 New infarction during follow-up¶9.4 (36)14.2 (248)0.01
  • Data are presented as percentages (counts) if not otherwise indicated.

  • * Fibrinolytic therapy and/or acute angioplasty and/or acute coronary artery bypass surgery.

  • Data available for 53% of the investigated patients #.

  • Rales, chock, given diuretics or continuous positive airway pressure therapy.

  • § In patients treated with reperfusion therapy (data available for 77%).

  • Patients followed for a minimum of 1 year and up to 10 years depending on admission date (mean 5.4 years).

  • h:m, hours:minutes; IV, intravenously; LV, left ventricular.