Baseline clinical characteristics
| All patients | Women | Men | p Value | |
| n=408 | n=215, 53% | n=193, 47% | ||
| Demographic data | ||||
| Age, years | 70.3±10.7 | 73.7±9.3 | 66.5±11.0 | <0.001 |
| Age >75 years | 152 (37.3) | 104 (48.4) | 48 (24.9) | <0.001† |
| Body mass index, kg/m2 | 27.3±4.5 | 27.3±5.1 | 27.3±3.8 | 0.926 |
| Body surface area, m2 | 1.87±0.21 | 1.77±0.20 | 1.99±0.17 | <0.001 |
| Clinical data | ||||
| NYHA functional class, mean±SD | 2.1±0.7 | 2.3±0.7 | 2.0±0.7 | <0.001‡ |
| Class I | 74 (18.2) | 30 (14.0) | 44 (23.0) | |
| Class II | 208 (51.2) | 97 (45.1) | 111 (58.1) | |
| Class III | 123 (30.3) | 87 (40.5) | 36 (18.9) | |
| Class IV | 1 (0.3) | 1 (0.5) | 0 (0.0) | |
| CCS class, mean±SD | 1.5±0.7 | 1.6±0.7 | 1.5±0.6 | 0.043† |
| CCS ≥III | 40 (9.9) | 27 (12.6) | 13 (6.8) | |
| Presyncope | 12 (2.9) | 9 (4.2) | 3 (1.6) | 0.116† |
| Syncope | 60 (14.7) | 35 (16.3) | 25 (13.0) | 0.344† |
| Dizziness during exercise | 57 (14.0) | 39 (18.4) | 18 (9.3) | 0.010† |
| EuroSCORE | 6.5±2.6 | 7.3±2.3 | 5.5±2.6 | <0.001 |
| Creatinine, mmol/l | 1.11±0.47 | 1.09±0.57 | 1.13±0.31 | 0.035* |
| History of coronary artery disease | 145 (35.8) | 71 (33.0) | 74 (39.0) | 0.215† |
| ≥2 Vessel disease | 58 (14) | 32 (15) | 26 (14) | 0.790† |
| Previous cardiac surgery | ||||
| LV dysfunction, EF ≤50% | 35 (8.6) | 13 (6.1) | 22 (11.4) | 0.054† |
| Systemic hypertension | 274 (67.3) | 162 (75.4) | 112 (58.3) | <0.001† |
| Diabetes | 79 (19.5) | 42 (19.5) | 37 (19.4) | 0.967† |
| Hypercholesterolaemia | 195 (48.0) | 103 (47.9) | 92 (48.2) | 0.958† |
| Peripheral vascular disease | 25 (6.1) | 8 (3.7) | 17 (8.8) | 0.032† |
| Pulmonary hypertension (>60 mm Hg) | 21 (5.2) | 13 (6.1) | 8 (4.2) | 0.386† |
| Chronic obstructive pulmonary disease | 37 (9) | 15 (7) | 22 (11) | 0.120† |
| Surgical priority | ||||
| Elective | 356 (97) | 184 (96) | 172 (98) | 0.2 |
| Emergent | 11 (3) | 8 (4) | 3 (2) | 0.2 |