Variable | Unadjusted | Adjusted | ||||
OR | 95% CI | p Value | OR | 95% CI | p Value | |
Age >60 years | 4.0 | 2.7 to 5.9 | <0.001 | 2.8 | 1.8 to 4.1 | <0.001 |
Female gender | 1.7 | 1.2 to 2.4 | 0.003 | 0.9 | 0.6 to 1.3 | 0.59 |
Previous infarction | 1.3 | 0.9 to 1.9 | 0.11 | – | – | – |
Diabetes | 1.1 | 0.8 to 1.6 | 0.59 | – | – | – |
Smoking | 0.9 | 0.8 to 1.2 | 0.95 | – | – | – |
History of hypertension | 1.8 | 1.3 to 2.4 | 0.008 | 1.1 | 0.7–1.5 | 0.74 |
eGFR <60 ml/minute | 2.5 | 1.8 to 3.5 | <0.001 | 1.2 | 0.8 to 1.8 | 0.37 |
Anterior infarction | 1.2 | 0.9 to 1.7 | 0.59 | – | – | – |
Killip class >I | 2.9 | 2.0 to 4.0 | <0.001 | 1.7 | 1.2 to 2.4 | 0.006 |
LVEF <45% | 2.3 | 1.6 to 3.2 | <0.001 | 2.1 | 1.2 to 3.6 | 0.007 |
Left atrial diameter >4 cm | 2.4 | 1.7 to 3.4 | <0.001 | 1.6 | 1.1 to 2.3 | 0.008 |
Coronary revascularisation | 1.3 | 0.8 to 2.3 | 0.33 | – | – | – |
FMR | ||||||
None/trivial | 1.0 (Referent) | – | – | 1.0 (Referent) | – | – |
Mild | 2.4 | 1.7 to 3.6 | <0.001 | 1.6 | 1.1 to 2.3 | 0.02 |
Moderate or severe | 4.4 | 2.7 to 7.2 | <0.001 | 2.1 | 1.2 to 3.6 | 0.007 |
↵* Variables with unadjusted p≥0.1 were not entered into the multivariable analysis. The final model adjusted for age, gender, estimated glomerular filtration rate (eGFR), history of hypertension, Killip class on admission, left atrial dimension and left ventricular ejection fraction (LVEF).
AF, atrial fibrillation; FMR, functional mitral regurgitation; OR, odds ratio.