Haemodynamic and vascular function at rest and peak exercise in patients with and without symptoms on exercise
| Asymptomatic N=28 | Symptomatic N=10 | p Value | |
| Rest | |||
| Heart rate (bpm) | 76±15 | 69±17 | 0.3 |
| SBP (mm Hg) | 134±18 | 136±16 | 0.5 |
| MAP (mm Hg) | 99±13 | 101±6 | 0.5 |
| Stroke index (ml/m2) | 39±8 | 42±17 | 0.6 |
| Cardiac index (l/min/m2) | 2.9±0.7 | 2.8±0.8 | 0.7 |
| VO2 (ml/kg/min) | 4.7±2.5 | 5.4±3.2 | 0.5 |
| SVR (dyne/s/cm−5) | 1520±497 | 1574±5 05 | 0.8 |
| Systemic arterial compliance (ml/m2/mm Hg) | 1.1±1.6 | 0.9±0.6 | 0.8 |
| Valvulo-arterial impedance (mm Hg/ml/m2) | 4.4±1.3 | 4.5±1.7 | 0.7 |
| Peak exercise | |||
| Exercise time (s) | 933±149 | 636±191 | <0.001 |
| SBP (mm Hg) | 156±13 | 150±21 | 0.4 |
| MAP (mm Hg) | 112±11 | 110±11 | 0.5 |
| Stroke index (ml/m2) | 44±11 | 35±10 | 0.024 |
| Cardiac index (l/min/m2) | 5.9±1.6 | 4.1±0.9 | 0.002 |
| VO2 (ml/kg/min) | 23.1±5.8 | 16.7±3.8 | 0.003 |
| SVR (dyne/s/cm−5) | 905±366 | 1161±243 | 0.02 |
| Systemic arterial compliance (ml/m2/mm Hg) | 0.7±0.2 | 0.6±0.2 | 0.4 |
| Cardiac power output (ml blood×mm Hg/min/) | 1269±458 | 868±238 | 0.001 |
| Circulatory power (ml O2×mm Hg/min) | 3606±899 | 2536±787 | 0.002 |
MAP, mean arterial pressure; O2, oxygen; SBP, systolic blood pressure; SVR, systemic vascular resistance; VO2, oxygen consumption.