Baseline characteristics according to treatment group
| Intensive glucose control (n=59) | Conventional glucose control (n=56) | p Value | |
| Age (years) | 66.9±12.0 | 67.5±12.2 | 0.77 |
| Male, n (%) | 37 (62.7) | 36 (64.3) | 0.86 |
| Risk factors, n (%) | |||
| Current smoking | 20 (33.9) | 15 (26.8) | 0.41 |
| Hypertension | 40 (67.8) | 42 (75.0) | 0.39 |
| Dyslipidaemia | 29 (49.2) | 29 (51.8) | 0.78 |
| Known diabetes mellitus | 39 (66.1) | 33 (60.0) | 0.50 |
| Obesity (BMI >30 kg/m2) | 20 (33.9) | 24 (42.9) | 0.32 |
| Medical history, n (%) | |||
| Previous MI | 13 (22.0) | 13 (23.2) | 0.88 |
| Previous PCI | 8 (13.6) | 11 (19.6) | 0.38 |
| Previous stroke | 2 (3.4) | 0 (0.0) | 0.26 |
| Symptomatic PVD | 7 (11.9) | 8 (14.3) | 0.70 |
| Chronic kidney disease | 5 (8.5) | 4 (7.1) | 0.53 |
| Previous diabetes mellitus treatment, n (%) | |||
| Metformin | 16 (27.1) | 12 (21.4) | 0.52 |
| Sulphonylureas | 10 (16.9) | 8 (14.3) | 0.80 |
| Others (thiazolidinediones, incretin mimetics) | 2 (3.4) | 1 (1.8) | 0.59 |
| Insulin | 12 (20.3) | 12 (21.4) | 0.89 |
| Clinical presentation, n (%) | |||
| STEMI | 33 (55.9) | 21 (37.5) | 0.05 |
| Anterior STEMI | 15 (25.4) | 8 (14.5) | 0.15 |
| Killip class ≥2 | 23 (39.0) | 24 (43.6) | 0.61 |
| GRACE score ≥140 | 37 (62.7) | 33 (60.0) | 0.77 |
| Laboratory data | |||
| Baseline glucose (mg/dl), median (IQR) | 181 (152–243) | 180 (140–223) | 0.92 |
| HbA1c (%) | 7.3±1.7 | 7.4±1.8 | 0.64 |
| Haematocrit (%) | 38.8±5.7 | 38.5±6.3 | 0.73 |
| Platelet count (1000/mm3) | 214.9±85.1 | 229.3±56.7 | 0.29 |
| Creatinine clearance (ml/min)* | 76.1±33.7 | 77.2±32.6 | 0.85 |
| Peak CK (UI/l), median (IQR) | 977 (318–2096) | 502 (165–1333) | 0.03 |
| Peak troponin I (ng/ml), median (IQR) | 25.7 (5.9–79.9) | 16.1 (4.8–33.3) | 0.08 |
| Angiographic characteristics, n (%) | |||
| Coronary angiography | 58 (98.3) | 54 (96.4) | 0.47 |
| No of narrowed (≥50%) coronary arteries | 1.7±0.7 | 1.7±0.8 | 0.97 |
| Left anterior descending | 33 (55.9) | 33 (60.0) | 0.66 |
| Left circumflex | 26 (44.1) | 30 (54.5) | 0.26 |
| Right coronary | 30 (50.8) | 35 (63.6) | 0.17 |
| Multivessel disease | 31 (52.5) | 33 (60.0) | 0.42 |
| No significant coronary narrowing | 6 (10.2) | 1 (1.8) | 0.07 |
↵* Assessed by de Crockcroft and Gault formula.
BMI, body mass index; CAD, coronary artery disease; CK, creatinine kinase; GRACE, Global Registry of Acute Cardiac Events; HbA1c, glycated haemoglobin A1c; MI, myocardial infarction; PCI, percutaneous coronary intervention; PVD, peripheral vascular disease; STEMI, ST-elevation myocardial infarction.