Area under the curve (AUC) of different backward regression models for the prediction of the primary endpoint at 1-year follow-up
| AUC | p Value for addition‡ | |
| Model 1: Classical cardiovascular risk factors* | 0.66 | Reference |
| Model 2: Model 1 + procedural risk factors† | 0.73 | 0.0001 |
| Model 3: Model 2 + residual platelet reactivity | ||
| DAPR as measured with AA- and 5 μmol/l ADP-induced LTA | 0.75 | 0.015 |
| DAPR as measured with AA- and 20 μmol/l ADP-induced LTA | 0.75 | 0.006 |
| DAPR as measured with the VerifyNow aspirin and P2Y12 assays | 0.80 | 0.009 |
↵* Age, hypertension, hypercholesterolaemia, left ventricular ejection fraction <45%, prior coronary artery bypass graft.
↵† Total stent length, number of lesions treated, number of stents implanted, left anterior descending artery stenting, graft stenting, bifurcation lesion, clopidogrel loading dose versus maintenance dose.
↵‡ Likelihood ratio test for additional value of platelet reactivity status (increase in AUC) as measured with multiple platelet function tests.
AA, arachidonic acid; DAPR, on-treatment platelet reactivity according to aspirin and clopidogrel test; LTA, light transmittance aggregometry.