Excluding studies (ref no) | No of remaining studies | OR (95% CI) | p Value | pheterogeneity | I2 |
Open-label20 27 | 8 | 0.89 (0.62 to 1.27) | 0.53 | 0.007 | 63.9% |
Intravenous PUFA preparation21 | 9 | 0.85 (0.59 to 1.22) | 0.37 | 0.002 | 66.5% |
Published as abstracts24 26–28 | 6 | 0.96 (0.63 to 1.46) | 0.86 | 0.02 | 63.8% |
Jadad score <327 28 | 8 | 0.91 (0.65 to 1.28) | 0.60 | 0.02 | 56.7% |
After removing two open-label studies; one study with intravenous omega-3 fatty acid preparation; four studies published only in abstract form or two studies with Jadad score less than 3, the analysis did not find a significant influence on the results.
PUFA, polyunsaturated fatty acids.