Congenital heart disease (per 1000 live births) | 1986–2006 | 1986–1999 | 2000–2006 | p Value | ||||||
(Live births: 1 592 232) | (Live births: 1 592 232) | (Live births: 677 483) | ||||||||
Born | Prenatal diagnosis | Born | Prenatal diagnosis | Born | Prenatal diagnosis | |||||
N | N | % | N | N | % | N | N | % | ||
Ventricular septal defect (2.56) | 6007 | 146 | 2.4 | 4076 | 48 | 1.2 | 1931 | 98 | 5.1 | <0.001 |
Atrial septal defect (0.53) | 1201 | 10 | 0.8 | 843 | 3 | 0 | 358 | 7 | 2 | 0.015 |
Aortic stenosis (0.48) | 1088 | 79 | 7.3 | 764 | 32 | 3.8 | 324 | 47 | 14.5 | <0.001 |
Pulmonary stenosis (0.36) | 816 | 26 | 3.2 | 573 | 8 | 1.4 | 243 | 18 | 7.4 | <0.001 |
Transposition of great arteries (0.33) | 748 | 87 | 11.6 | 525 | 30 | 5.7 | 223 | 57 | 25.6 | <0.001 |
Coarctation of aorta (0.33) | 748 | 58 | 7.8 | 525 | 14 | 2.7 | 223 | 44 | 19.7 | <0.001 |
Atrioventricular septal defect (0.25) | 567 | 243 | 42.9 | 398 | 102 | 25.6 | 169 | 141 | 83.4 | <0.001 |
Hypoplastic left heart (0.21) | 476 | 241 | 50.6 | 334 | 105 | 31.4 | 142 | 136 | 95.8 | <0.001 |
Tetralogy of Fallot (0.21) | 476 | 83 | 17.6 | 334 | 30 | 9 | 142 | 53 | 37.3 | <0.001 |
Pulmonary atresia (0.13) | 295 | 97 | 32.8 | 207 | 37 | 17.9 | 88 | 60 | 68.2 | <0.001 |
Double-outlet right ventricle (0.08) | 181 | 140 | 77.3 | 127 | 68 | 53.5 | 54 | 72 | 133.3 | * |
Univentricular heart (0.08) | 181 | 77 | 42.5 | 127 | 50 | 39.4 | 54 | 27 | 50 | 0.246 |
Persistent arterial trunk (0.07) | 159 | 61 | 38.4 | 112 | 23 | 20.5 | 47 | 38 | 80.8 | 0.272 |
Total anomalous pulmonary venous connection (0.05) | 113 | 0 | 0 | 80 | 0 | 0 | 33 | 0 | 0 | 1 |
Tricuspid atresia (0.05) | 113 | 54 | 47.8 | 80 | 24 | 30 | 33 | 30 | 90.9 | <0.001 |
Ebstein anomaly (0.03) | 68 | 34 | 50 | 48 | 20 | 41.7 | 20 | 14 | 70 | 0.062 |
Interrupted aortic arch (0.02) | 45 | 12 | 26.7 | 32 | 3 | 9.4 | 13 | 9 | 69.2 | <0.001 |
Anomalous origin of left coronary artery from pulmonary trunk (0.01) | 23 | 0 | 0 | 16 | 0 | 0 | 7 | 0 | 0 | 1 |
↵* Not calculated (see text).