Troponin ratio 0.01 to ≤1 (n=6328) | Troponin ratio >1 to ≤10 (n=4422) | Troponin ratio >10 to ≤100 (n=4057) | Troponin ratio >100 to ≤1000 (n=1403) | Troponin ratio >1000 (n=107) | p Value for trend* | |
New-onset congestive heart failure (%)† | 142/5664 (2.5) | 190/3694 (5.1) | 243/3271 (7.4) | 124/1068 (11.6) | 12/76 (15.8) | <0.001 |
Cardiogenic shock (%)‡ | 28/6019 (0.5) | 59/4211 (1.4) | 80/3941 (2.0) | 60/1373 (4.4) | 13/102 (12.7) | <0.001 |
Cardiac arrest/VF or sustained VT (%)‡ | 65/6217 (1.0) | 104/4305 (2.4) | 133/3954 (3.4) | 80/1353 (5.9) | 13/97 (13.4) | <0.001 |
Death (%) | 53/6328 (0.8) | 98/4422 (2.2) | 123/4057 (3.0) | 74/1403 (5.3) | 15/107 (14.0) | <0.001 |
Recurrent MI (%) | 98/6294 (1.6) | 102/4389 (2.3) | 92/4011 (2.3) | 21/1392 (1.5) | 6/103 (5.8) | 0.035 |
Death or recurrent MI (%) | 141/6295 (2.2) | 184/4393 (4.2) | 199/4013 (5.0) | 91/1392 (6.5) | 20/103 (19.4) | <0.001 |
↵* Cochran–Armitage, two-sided test for linear trend. Note p values remain unchanged if the highest troponin group is excluded from the test, with the exception of recurrent myocardial infarction (MI), where the p value becomes 0.13.
↵† Analysis for new-onset congestive heart failure was confined to patients with no signs or symptoms of heart failure.
↵‡ Analysis for cardiogenic shock was confined to patients who did not present with cardiogenic shock, and analysis for cardiac arrest/ventricular fibrillation (VF) or sustained ventricular tachycardia (VT) was confined to patients who did not present with cardiac arrest.