Diagnostic accuracy results of echocardiography versus right heart catheterisation for each study
| Study | N | TP | FN | FP | TN | Sensitivity | Specificity | ECHO threshold (mm Hg) | RHC threshold (mm Hg)† |
| Cardiac disease | |||||||||
| Lanzarini et al29 | 57§ | 31 | 4 | 0 | 22 | 88% | 100% | sPAP ≥32 | sPAP ≥35 and mPAP ≥20 |
| Mogollon et al38 | 67 | 34 | 4 | 16 | 13 | 89% | 46% | sPAP ≥40 | mPAP >35 |
| Penning et al41 | 27 | 14 | 3 | 9 | 1 | 82% | 10% | sPAP ≥40 | sPAP ≥35 |
| Lung disease | |||||||||
| Mixed causes | |||||||||
| Arcasoy et al31 | 166 | 51 | 9 | 48 | 58 | 85% | 55% | sPAP ≥45 | sPAP ≥45 |
| Idiopathic pulmonary fibrosis | |||||||||
| Nathan et al40 | 60 | 16 | 6 | 21 | 17 | 73% | 45% | sPAP ≥40 | mPAP >25 |
| Scleroderma | |||||||||
| Denton et al32 | 20 | 15 | 0 | 2 | 3 | 100% | 60% | sPAP ≥30 | sPAP ≥30‡ |
| Hsu et al34 | 49 | 14 | 10 | 1 | 24 | 58% | 96% | sPAP ≥47 | mPAP ≥25‡ |
| Mukerjee et al39 | 137 | 58 | 42 | 5 | 32 | 58% | 87% | sPAP ≥40 | mPAP ≥25 |
| COPD | |||||||||
| Fisher et al33 | 74* | 21 | 14 | 10 | 29 | 60% | 74% | sPAP ≥40 | mPAP ≥25 |
| Laaban et al36 | 27 | 17 | 1 | 3 | 6 | 94% | 67% | sPAP ≥35 | sPAP ≥35 |
| Matsuyama et al37 | 35 | 23 | 5 | 1 | 6 | 83% | 86% | sPAP ≥40 | mPAP >25 |
| Mixed cardiac and lung disease | |||||||||
| Kim et al35 | 74 | 29 | 1 | 10 | 34 | 97% | 77% | sPAP ≥50 | mPAP ≥35 |
↵* 63 Patients but 74 paired echocardiogram (ECHO)/right heart catheterisation (RHC) results.
↵† At rest.
↵‡ Normal pulmonary capillary wedge pressure.
↵§ Test patient population.
COPD, chronic obstructive pulmonary disease; FN, false negative; FP, false positive; mPAP, mean pulmonary arterial pressure; N, number of patients; sPAP, systolic pulmonary arterial pressure; TN, true negative; TP, true positive.