Sensitivity analysis for the correlation and diagnostic accuracy meta-analyses
| Sensitivity analysis for correlation meta-analysis (n=27) | |||
| Study characteristic | n | Correlation coefficient | I2 |
| Prospective studies | 21 | 0.72 (95% CI 0.69 to 0.75) | 99% (95% CI 85 to 99) |
| Retrospective studies | 6 | 0.61 (95% CI 0.54 to 0.69) | 82% (95% CI 69 to 94) |
| Study year ≥2000 | 18 | 0.65 (95% CI 0.61 to 0.68) | 99% (95% CI 70 to 93) |
| Study year <2000 | 9 | 0.88 (95% CI 0.84 to 0.91) | 94% (95% CI 79 to 96) |
| Cardiac population | 8 | 0.74 (95% CI 0.69 to 0.79) | 99% (95% CI 78 to 99) |
| Lung population | 15 | 0.64 (95% CI 0.60 to 0.68) | 99% (95% CI 76 to 99) |
| Mixed population | 4 | 0.84 (95% CI 0.80 to 0.89) | 85% (95% CI 74 to 90) |
| <7 Days between ECHO and RHC | 15 | 0.76 (95% CI 0.73 to 0.79) | 99% (95% CI 88 to 99) |
| <1 Month between ECHO and RHC | 21 | 0.71 (95% CI 0.68 to 0.75) | 99% (95% CI 89 to 99) |
| RAP calculated using IVC | 19 | 0.65 (95% CI 0.62 to 0.69) | 99% (95% CI 87 to 99) |
| RAP calculated using JVP | 6 | 0.89 (95% CI 0.85 to 0.93) | 92% (95% CI 86 to 96) |
| RAP calculated using fixed value | 2 | 0.74 (95% CI 0.64 to 0.84) | 72% (95% CI 69 to 87) |
| Sensitivity analysis for diagnostic accuracy meta-analysis (n=12) | |||||
| Study characteristic | n | Sensitivity | Specificity | I2 | |
| Prospective studies | 9 | 0.84 (95% CI 0.70 to 0.92) | 0.81 (95% CI 0.64 to 0.90) | 87% (95% CI 69 to 94) | 84% (95% CI 74 to 92) |
| Study year ≥2000 | 9 | 0.79 (95% CI 0.67 to 0.87) | 0.76 (95% CI 0.50 to 0.91) | 80% (95% CI 79 to 92) | 88% (95% CI 77 to 93) |
| Cardiac population | 3 | 0.90 (95% CI 0.83 to 0.94) | 0.69 (95% CI 0.15 to 0.97) | 73% (95% CI 64 to 82) | 91% (95% CI 79 to 94) |
| Lung population | 8 | 0.77 (95% CI 0.64 to 0.86) | 0.70 (95% CI 0.52 to 0.83) | 79% (95% CI 69 to 84) | 81% (95% CI 76 to 91) |
| <7 Days between ECHO and RHC | 5 | 0.87 (95% CI 0.73 to 0.95) | 0.85 (95% CI 0.59 to 0.96) | 82% (95% CI 65 to 87) | 90% (95% CI 78 to 92) |
| <1 Month between ECHO and RHC | 7 | 0.84 (95% CI 0.70 to 0.92) | 0.77 (95% CI 0.45 to 0.93) | 80% (95% CI 73 to 90) | 88% (95% CI 77 to 92) |
| RAP calculated using IVC | 9 | 0.81 (95% CI 0.71 to 0.88) | 0.69 (95% CI 0.46 to 0.85) | 82% (95% CI 74 to 88) | 86% (95% CI 78 to 90) |
ECHO, echocardiography; IVC, inferior vena cava; n, number of studies; RAP, right atrial pressure; RHC, right heart catheterisation.