Baseline characteristics for symptomatic patients included in the REACH Registry Europe according to ‘good control’ or ‘poor control’ of their cardiovascular risk factors
| Total | Good control | Poor control | p Value | |
| No of patients | 20 588 | 12236 (59.4%) | 8340 (40.5%) | |
| Demographics | ||||
| Age (ears) | 67.0±9.8 | 67.2±9.9 | 66.7±9.7 | <0.001 |
| Female | 29.4 | 27.0 | 32.9 | <0.0001 |
| BMI (kg/m2) | 27.8±4.5 | 27.5±4.3 | 28.3±4.7 | <0.0001 |
| Caucasian (%) | 73.0 | 71.7 | 74.9 | <0.0001 |
| University education (%) | 14.6 | 15.3 | 13.6 | <0.001 |
| Disease territory | ||||
| CAD (%) | 70.6 | 75.4 | 63.4 | <0.0001 |
| CVD (%) | 34.2 | 29.9 | 40.4 | <0.0001 |
| PAD (%) | 20.8 | 17.1 | 26.2 | <0.0001 |
| Polyvascular (%) | 22.7 | 20.4 | 26.0 | <0.0001 |
| Cardiovascular risk factors | ||||
| Seated SBP, mean±SD (mm Hg) | 141.1±19.6 | 132.6±16.2 | 153.5±17.4 | <0.0001 |
| Seated DBP, mean±SD (mm Hg) | 81.5±10.9 | 77.2±8.7 | 88.0±10.6 | <0.0001 |
| SBP ≥140/DBP ≥90 mm Hg (%) | 26.0 | 5.7 | 56.0 | <0.0001 |
| Treated hypertension (%) | 78.2 | 72.9 | 85.9 | <0.0001 |
| Fasting blood glucose (mg/dl), mean±SD | 113.8±39.6 | 106.6±33.4 | 127.5±46.2 | <0.0001 |
| Fasting blood glucose ≥127 mg/dl (%) | 23.1 | 15.7 | 37.2 | <0.0001 |
| Type I or II diabetes in treatment (%) | 28.0 | 23.1 | 35.2 | <0.0001 |
| Fasting total cholesterol (mg/dl), mean±SD | 205.3±49.0 | 191.8±43.2 | 231.1±49.1 | <0.0001 |
| Total cholesterol ≥190 mg/dl (%) | 60.7 | 47.8 | 85.3 | <0.0001 |
| Fasting triglycerides (mg/dl), mean±SD | 160.2 ± 93.9 | 146.4 ± 83.8 | 187.4 ± 105.8 | <0.0001 |
| Hypercholesterolaemia in treatment (%) | 67.1 | 69.2 | 64.1 | <0.0001 |
| Former smoker (%) | 43.1 | 49.8 | 32.8 | <0.0001 |
| Current smoker (%) | 17.2 | 8.7 | 30.3 | <0.0001 |
| Never smoked (%) | 39.7 | 41.5 | 36.8 | <0.0001 |
| Current or former smoker (%) | 60.3 | 58.5 | 63.2 | <0.0001 |
| Previous history of CAD | ||||
| Stable angina (%) | 40.5 | 40.7 | 40.1 | 0.40 |
| Unstable angina (%) | 16.8 | 17.8 | 15.3 | <0.0001 |
| MI (%) | 39.7 | 44.6 | 32.5 | <0.0001 |
| Coronary angioplasty/stenting (%) | 26.4 | 31.0 | 19.8 | <0.0001 |
| Coronary artery bypass graft (%) | 18.9 | 22.1 | 14.2 | <0.0001 |
| Previous history of CVD | ||||
| Documented TIA (%) | 17.9 | 15.1 | 22.0 | <0.0001 |
| Ischaemic stroke (%) | 23.4 | 20.7 | 27.3 | <0.0001 |
| Previous history of PAD | ||||
| Intermittent claudication associated with | ||||
| ABI <0.90 (%) | 23.4 | 18.6 | 30.5 | <0.0001 |
| Lower limb graft (%) | 10.5 | 9.4 | 12.2 | <0.0001 |
| Amputation (lower limb) (%) | 2.5 | 1.9 | 3.3 | <0.0001 |
| Past medical history | ||||
| Carotid angioplasty/stenting (%) | 2.2 | 2.2 | 2.2 | 0.87 |
| Carotid surgery (%) | 4.2 | 4.4 | 4.0 | 0.22 |
| Congestive heart failure (%) | 16.7 | 16.9 | 16.5 | 0.40 |
| Abdominal aortic aneurysm (%) | 2.9 | 2.9 | 2.7 | 0.39 |
| Geographical origin | ||||
| Western Europe (%) | 73.9 | 76.2 | 70.5 | <0.0001 |
| Eastern Europe (%) | 26.1 | 23.8 | 29.5 | <0.0001 |
| Physician profile | ||||
| Generalist (%) | 36.1 | 39.1 | 31.8 | <0.0001 |
| Internist (%) | 27.6 | 28.2 | 26.7 | <0.05 |
| Cardiologist (%) | 26.3 | 29.1 | 22.2 | <0.0001 |
| Vascular medicine (%) | 7.1 | 5.2 | 9.8 | <0.0001 |
| Surgeon (%) | 3.3 | 2.2 | 5.0 | <0.0001 |
| Neurologist (%) | 14.5 | 10.7 | 20.0 | <0.0001 |
| Endocrinologist | 2.8 | 2.8 | 2.9 | 0.71 |
| Other (%) | 5.8 | 5.6 | 6.1 | 0.11 |
Cardiovascular risk factors are considered controlled when at the following target levels: systolic blood pressure (SBP) <140 mm Hg, diastolic blood pressure (DBP) <90 mm Hg, glycaemia <1.1 g/l, total cholesterol <2.0 g/l, non-smoking; ‘good control’, 3–5 risk factors at target; ‘poor control’, 0–2 risk factors at target.
ABI, ankle–brachial index; BMI, body mass index; CAD, coronary artery disease; CVD, cardiovascular disease; MI, myocardial infarction; PAD, peripheral artery disease; TIA, transient ischaemic attack.