Table 2

Frequency of HPR stratified by CYP2C19 genotype

CYP2C19*2 genotype*1/*1*1/*2*2/*2p Value
5 μmol/l ADP-induced LTA >42.9%38%53%70%<0.001
20 μmol/l ADP-induced LTA >64.5%31%52%78%<0.001
PlateletWorks >80.5%33%51%91%<0.001
VerifyNow >236 PRU34%49%67%<0.001
  • χ2 test was used to test the statistical significance of differences in the frequency of HPR in the different CYP2C19 genotypes *1/*1, *1/*2 and *2/*2.

  • HPR, high on-treatment platelet reactivity; LTA, light transmittance aggregometry; PRU, P2Y12 reaction units.