Table 4

Echocardiography dimensions and diastolic indices of conventional Doppler and tissue Doppler imaging echocardiography at follow-up

ParametersFollow-up patients without HFNEFFollow-up patients with HFNEFp Value
Heart dimensions
 LVEF, Simpson (%)64.0 (63.0–68.0)64.0 (59.0–68.0)0.42
 LA parasternal, mm38.0 (37.0–40.0)36.5 (33.0–42.0)0.33
 LVEDD, mm52.0 (49.0–55.0)49.0 (45.0–52.0)0.05
 LVESD, mm32.0 (27.0–35.0)31.0 (27.0–33.5)0.48
 Septum, mm11.0 (10.0–11.0)10.0 (9.0–11.5)0.57
 Posterior wall, mm11.0 (10.0–11.0)11.0 (9.0–11.0)0.57
 LVOT, m/s1.0 (0.92–1.10)1.0 (0.95–1.13)0.79
Conventional Doppler
 E, m/s0.7 (0.63–0.84)0.81 (0.71–0.94)0.16
 A, m/s0.61 (0.47–0.7)0.84 (0.74–0.99)0.001
 E/A1.12 (1.03–1.42)0.97 (0.81–1.18)0.012
 IVRT, ms85.6 (73.9–95.6)102.7 (91.3–107.9)0.0024
 DT, ms205 (180–216)241 (205–255)0.02
Tissue Doppler
 Slateral, m/s0.08 (0.06–0.09)0.07 (0.05–0.08)0.09
 E′lateral, m/s0.09 (0.08–0.11)0.07 (0.06–0.08)0.006
 A′lateral, m/s0.07 (0.05–0.09)0.07 (0.06–0.08)0.9
 E′/A′lateral1.43 (0.87–1.95)0.92 (0.61–1.3)0.03
 E/E′lateral7.9 (6.9–8.9)9.4 (8.3–16.9)0.006
 S′septal, m/s0.06 (0.06–0.07)0.06 (0.05–0.06)0.07
 E′septal, m/s0.09 (0.08–0.11)0.07 (0.06–0.09)0.03
 A′septal, m/s0.07 (0.06–0.09)0.07 (0.07–0.08)0.9
 E′/A′septal1.19 (0.98–1.45)0.9 (0.75–1.25)0.04
 E/E′septal6.8 (6.4–9.1)10.9 (9.3–13.8)0.001
 E/E′mean7.4 (6.8–9.8)10.8 (9.5–14.4)0.001
  • Values are expressed as the median (25–75% quartile).

  • A′, late diastolic velocity; DT, deceleration time; E′, early diastolic peak velocity; E/A, ratio of peak early and late mitral flow; E/E′, ratio of transmitral flow velocity to annular velocity; HFNEF, heart failure with a normal ejection fraction; IVRT, isovolumic relaxation time; LA, left atrium; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; LVOT, left ventricular outflow tract; S′, systolic peak velocity.