Table 2

Clinical outcomes

EPO, n=26 (22 with acute CMR)Placebo, n=25 (19 with acute CMR)Difference (95% CI)p Value
Initial blood results, myocardial area at risk and CMR scan
24 h troponin T AUC (μg/l)114.6100.813.81 (−29.69 to 57.31)0.526
24 h CK-MB AUC (U/l)4682.33649.11033.2 (−562.7 to 2629.1)0.199
BARI score (%)2933−3.8 (−8.6 to 1.0)0.12
APPROACH score (%)3031−0.8 (−6.8 to 5.2)0.8
Infarct-ESA by CMR (%)28270.8 (−5.4 to 7.0)0.8
Myocardial infarct mass (g)32.825.47.46 (−2.76 to 17.69)0.148
Myocardial salvage index0.380.47−0.09 (−0.28 to 0.10)0.333
Microvascular obstruction (%)81.847.434.4 (6.8–62.1)0.020
LVEDVi (ml/m2)84.473.011.40 (4.05–18.75)0.003
LVESVi (ml/m2)41.334.66.77 (0.45–13.09)0.036
LVSVi (ml/m2)43.138.44.63 (−0.44 to 9.70)0.072
LVMi (g/m2)89.279.49.78 (0.94–18.63)0.031
LVEF (%)51.353.2−1.87 (−7.40 to 3.66)0.499
4-month follow-up CMR endpoints
 LVEDVi (ml/m2)88.184.43.74 (−10.11 to 17.58)0.586
 LVESVi (ml/m2)42.736.46.30 (−6.60 to 19.21)0.327
 LVSVi (ml/m2)45.448.0−2.56 (−8.24 to 3.11)0.364
 LVMi (g/m2)82.475.07.33 (−5.00 to 19.56)0.235
 LVEF (%)52.659.1−6.46 (−13.94 to 1.01)0.088
 Myocardial infarct mass (g)17.712.45.31 (−0.57 to 11.19)0.075
Clinical outcomes
 Death01
 Stroke00
 Unplanned revascularisation10
 Planned revascularisation22
 Emergency admission to hospital51
 LV thrombus10
  • Values are mean (SD).

  • AUC, area under the curve; LVEDVi, indexed left ventricle end-diastolic volume; LVESVi, indexed left ventricle end-systolic volume; LVSVi, indexed left ventricle stroke volume; LVMi, indexed left ventricle mass; LVEF, LV ejection fraction.