Multivariable competing risk analysis for the risk of SCD and incident CHD associated with different demographic and clinical variables
| Characteristic | Definite SCD | Incident CHD | p Value† |
| HR (95% CI)* | HR (95% CI)* | ||
| ARIC study (vs CHS) | 1.09 (0.62 to 1.89) | 0.84 (0.70 to 1.00) | 0.3889 |
| Age (per decade)‡ | 2.61 (1.71 to 3.97) | 1.75 (1.53 to 2.01) | 0.0788 |
| Male sex (vs female) | 2.42 (1.77 to 3.30) | 2.03 (1.84 to 2.24) | 0.2930 |
| Black race/ethnicity (vs non-black) | 1.81 (1.31 to 2.49) | 0.76 (0.67 to 0.86) | <0.0001 |
| BMI | 0.0220 | ||
| BMI (kg/m2) | 0.49 (0.23 to 1.03) | 1.14 (0.79 to 1.63) | |
| BMI2 (kg/m2) | 1.07 (1.01 to 1.13) | 0.99 (0.96 to 1.02) | |
| Smoking status (vs current) | 0.7477 | ||
| Never | 0.59 (0.40 to 0.86) | 0.69 (0.61 to 0.78) | |
| Former | 0.70 (0.48 to 1.01) | 0.76 (0.68 to 0.85) | |
| Diabetes | 2.54 (1.84 to 3.50) | 2.08 (1.86 to 2.32) | 0.2470 |
| Hypertension | 2.17 (1.60 to 2.93) | 1.57 (1.43 to 1.72) | 0.0460 |
| LDL-cholesterol (mg/dl) | 1.12 (0.98 to 1.29) | 1.27 (1.22 to 1.33) | 0.0869 |
| HDL-cholesterol (mg/dl) | 0.92 (0.76 to 1.11) | 0.80 (0.75 to 0.86) | 0.1880 |
| Triglycerides (mg/dl) | 0.99 (0.85 to 1.15) | 1.06 (1.02 to 1.11) | 0.3517 |
| White blood cell count (×103/μl) | 1.27 (1.11 to 1.46) | 1.15 (1.11 to 1.21) | 0.1759 |
* Unless described otherwise, HRs for continuous variables are per 1 SD increase and for the abnormal value for the categorical variables adjusted for the rest of the variables in the table.
† Assessing equivalence of HRs for the two end points.
‡ For age, timescale is time since study entry; for all other variables, timescale is age.
BMI, body mass index; CHD, coronary heart disease; LDL, low-density lipoprotein; HDL, high-density lipoprotein; SCD, sudden cardiac death.