Table 1

Patient characteristics, comorbid conditions and echocardiographic indices

Severe AS (n=108)Very severe AS (n=58)p Value
Age, years, mean±SD70±1170±110.88
Female, n (%)65 (60)31 (53)0.40
Symptoms, n (%)52 (48)38 (66)0.03
 Chest pain7 (6)7 (12)0.23
 Syncope3 (3)3 (5)0.44
 NYHA ≥33 (3)5 (9)0.10
Comorbidities
 Atrial fibrillation, n (%)23 (21)8 (14)0.23
 Ischaemic heart disease, n (%)22 (20)9 (16)0.44
 Previous cerebral infarction, n (%)13 (12)3 (5)0.13
 Chronic kidney disease, n (%)48 (44)28 (48)0.64
 Haemodialysis, n (%)3 (3)1 (2)0.66
 Chronic obstructive pulmonary disease, n (%)5 (5)1 (2)0.31
 Logistic EuroSCORE8.5±7.97.1±6.00.25
 STS risk score2.5±2.13.0±2.40.22
Echocardiographic indices
 LVEF, %65±865±80.68
 Left ventricular end-diastolic dimension, mm44±644±60.91
 Left ventricular end-systolic dimension, mm26±626±60.85
 Aotic valve area, cm20.89±0.130.63±0.20<0.001
 Aortic jet velocity, m/s3.8±0.55.0±0.8<0.001
 Aortic valve area index, cm2/m20.60±0.100.42±0.12<0.001
 Mean aortic gradient, mm Hg37±962±18<0.001
 Right ventricular systolic pressure, mm Hg37±739±80.22
  • AS, aortic stenosis; EuroSCORE, European system for cardiac operative risk evaluation; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association functional class; STS, Society of Thoracic Surgeons.