Total population | Propensity-matched population | |||||
Low HDL-C (n=1585) | High HDL-C (n=1108) | p Value | Low HDL-C (n=990) | High HDL-C (n=990) | p Value | |
Age, years | 62.7±10.6 | 62.2±10.8 | 0.226 | 62.0±10.4 | 62.1±10.8 | 0.899 |
Age ≥65 years | 776 (49.0) | 507 (45.8) | 0.108 | 453 (45.8) | 449 (45.4) | 0.857 |
Male | 947 (59.7) | 833 (75.2) | <0.001 | 716 (72.3) | 717 (72.4) | 0.960 |
Body mass index, kg/m2 | 25.0±3.1 | 24.4±3.1 | <0.001 | 24.6±2.8 | 24.6±3.0 | 0.648 |
Clinical presentation | 0.002 | 0.757 | ||||
Stable angina | 719 (45.4) | 576 (52.0) | 482 (48.7) | 485 (49.0) | ||
Unstable angina | 387 (24.4) | 236 (21.3) | 238 (24.0) | 225 (22.7) | ||
AMI | 479 (30.2) | 296 (26.7) | 270 (27.3) | 280 (28.3) | ||
Hypertension | 993 (62.6) | 629 (56.8) | 0.002 | 579 (58.5) | 579 (58.5) | 1.000 |
Diabetes mellitus | 650 (41.0) | 340 (30.7) | <0.001 | 349 (35.3) | 330 (33.3) | 0.368 |
Current smoker | 373 (23.6) | 290 (26.2) | 0.123 | 249 (25.2) | 260 (26.3) | 0.572 |
Chronic kidney disease | 68 (4.3) | 35 (3.2) | 0.153 | 28 (2.8) | 34 (3.4) | 0.439 |
Family history of CAD | 75 (4.7) | 60 (5.4) | 0.421 | 51 (5.2) | 52 (537) | 0.919 |
Prior MI | 69 (4.4) | 39 (3.5) | 0.318 | 40 (4.0) | 37 (3.7) | 0.727 |
Prior PCI | 101 (6.4) | 69 (6.4) | 0.936 | 44 (4.4) | 46 (4.6) | 0.829 |
Prior CABG | 11 (0.7) | 15 (1.4) | 0.108 | 10 (1.0) | 11 (1.1) | 0.826 |
Prior stroke | 116 (7.3) | 73 (6.6) | 0.491 | 77 (7.8) | 67 (6.8) | 0.387 |
LVEF, %* | 59.2 | 60.4 | 0.003 | 60.1±9.4 | 60.2±9.2 | 0.797 |
LVEF <50% | 219 (15.6) | 119 (12.2) | 0.020 | 111 (11.2) | 109 (11.0) | 0.943 |
Data are presented as mean±SD or n (%).
↵* Left ventricular ejection fraction (LVEF) was available for 2385 patients.
AMI, acute myocardial infarction; CABG, coronary artery bypass graft; CAD, coronary artery disease; HDL-C, high-density lipoprotein cholesterol; MI, myocardial infarction; PCI, percutaneous coronary intervention.