Table 1

Baseline clinical characteristics at index PCI according to follow-up HDL-C level

Total populationPropensity-matched population
Low HDL-C (n=1585)High HDL-C (n=1108)p ValueLow HDL-C (n=990)High HDL-C (n=990)p Value
Age, years62.7±10.662.2±10.80.22662.0±10.462.1±10.80.899
Age ≥65 years776 (49.0)507 (45.8)0.108453 (45.8)449 (45.4)0.857
Male947 (59.7)833 (75.2)<0.001716 (72.3)717 (72.4)0.960
Body mass index, kg/m225.0±3.124.4±3.1<0.00124.6±2.824.6±3.00.648
Clinical presentation0.0020.757
 Stable angina719 (45.4)576 (52.0)482 (48.7)485 (49.0)
 Unstable angina387 (24.4)236 (21.3)238 (24.0)225 (22.7)
 AMI479 (30.2)296 (26.7)270 (27.3)280 (28.3)
 Hypertension993 (62.6)629 (56.8)0.002579 (58.5)579 (58.5)1.000
 Diabetes mellitus650 (41.0)340 (30.7)<0.001349 (35.3)330 (33.3)0.368
 Current smoker373 (23.6)290 (26.2)0.123249 (25.2)260 (26.3)0.572
 Chronic kidney disease68 (4.3)35 (3.2)0.15328 (2.8)34 (3.4)0.439
 Family history of CAD75 (4.7)60 (5.4)0.42151 (5.2)52 (537)0.919
 Prior MI69 (4.4)39 (3.5)0.31840 (4.0)37 (3.7)0.727
 Prior PCI101 (6.4)69 (6.4)0.93644 (4.4)46 (4.6)0.829
 Prior CABG11 (0.7)15 (1.4)0.10810 (1.0)11 (1.1)0.826
 Prior stroke116 (7.3)73 (6.6)0.49177 (7.8)67 (6.8)0.387
 LVEF, %*59.260.40.00360.1±9.460.2±9.20.797
 LVEF <50%219 (15.6)119 (12.2)0.020111 (11.2)109 (11.0)0.943
  • Data are presented as mean±SD or n (%).

  • * Left ventricular ejection fraction (LVEF) was available for 2385 patients.

  • AMI, acute myocardial infarction; CABG, coronary artery bypass graft; CAD, coronary artery disease; HDL-C, high-density lipoprotein cholesterol; MI, myocardial infarction; PCI, percutaneous coronary intervention.