Table 4

Correlations between MMPs, TIMPs, MPO and measures of left ventricular dysfunction and remodelling

LVEF% at 5 days (n=58)LVEF% at 4 months (n=46)dEDVI (n=46)dESVI (n=46)
MMP-2
 0 h−0.332*−0.296*−0.091−0.056
 12 h−0.412**−0.403**−0.123−0.151
 24 h−0.260−0.245−0.033−0.001
 48 h−0.202−0.2030.0310.152
MMP-8
 0 h−0.113−0.1830.022−0.195
 12 h−0.119−0.207−0.322*−0.273
 24 h−0.055−0.024−0.020−0.080
 48 h−0.100−0.193−0.125−0.282
MMP-9
 0 h−0.247−0.260−0.039−0.204
 12 h−0.264−0.258−0.288−0.207
 24 h−0.110−0.0450.033−0.027
 48 h−0.130−0.230−0.105−0.228
TIMP-1
 0 h−0.257−0.228−0.174−0.076
 12 h−0.249−0.168−0.231−0.096
 24 h−0.368*−0.345*−0.261−0.261
 48 h−0.356*−0.270−0.305*−0.185
TIMP-2
 0 h−0.334*−0.2360.0010.092
 12 h−0.359*−0.328*0.0440.088
 24 h−0.176−0.211−0.0190.015
 48 h−0.164−0.267−0.0430.092
MPO
 0 h−0.214−0.167−0.155−0.204
 12 h−0.092−0.117−0.198−0.134
 24 h−0.112−0.014−0.109−0.033
 48 h−0.212−0.313*−0.199−0.347*
  • *p<0.05, **p<0.01.

  • Values are given as ρ values from the Spearman test.

  • dEDVI, change in end-diastolic volume index from 5 days to 4 months; dESVI, change in end-systolic volume index from 5 days to 4 months; LVEF, left ventricular ejection fraction; MMP, matrix metalloproteinase; MPO, myeloperoxidase; n, number of patients; TIMP, tissue inhibitor of metalloproteinase.