Table 1

Major cost parameters (2010 prices in £)

Drug costs	Per day	Source
Dabigatran etexilate	2.52	24
Warfarin (5 mg)	0.04	24
Aspirin (162.5 mg)	0.09	24

Monitoring costs	Per annum	Source
International normalised ratio monitoring	414.90	25

Event costs	Per acute event	Source
Ischaemic stroke, fatal	3059	27
Ischaemic stroke, independent	3401	27
Ischaemic stroke, moderate disability	17 743	27
Ischaemic stroke, totally dependent	24 234	27
Systemic embolism, fatal	400	Assumption
Systemic embolism, non-fatal	2373	26
Transient ischaemic attack	1064	26
Intracranial haemorrhage or haemorrhagic stroke, fatal	3059	27
Intracranial haemorrhage or haemorrhagic stroke, independent	3401	27
Intracranial haemorrhage or haemorrhagic stroke, moderate disability	17 743	27
Intracranial haemorrhage or haemorrhagic stroke, totally dependent	24 234	27
Extracranial haemorrhage, fatal	1852	26
Extracranial haemorrhage (gastrointestinal), non-fatal	1594	26
Extracranial haemorrhage (non-gastrointestinal), non-fatal	2109	26
Minor bleed	84	25
Acute myocardial infarction	2956	26

Follow-up costs	Per Quarter	Source
Independent with stroke history	331	27
Moderate disability with stroke history	2868	27
Dependent disability with stroke history	6089	27