30 day outcomes | 1 year outcomes | |||||||
Unadjusted | Adjusted | Unadjusted | Adjusted | |||||
HR (95% CI) | p Value | HR (95% CI) | p Value | HR (95% CI) | p Value | HR (95% CI) | p Value | |
CV death | 4.67 (2.85 to 7.67) | <0.001 | 2.32 (1.30 to 4.17) | 0.005 | 3.85 (2.92 to 5.08) | <0.001 | 1.85 (1.33 to 2.59) | <0.001 |
Severe recurrent ischemia | 1.23 (0.90 to 1.69) | 0.19 | 0.93 (0.65 to 1.33) | 0.69 | 1.16 (0.95 to 1.40) | 0.14 | 1.04 (0.83 to 1.29) | 0.73 |
MI | 1.57 (1.13 to 2.17) | 0.006 | 1.11 (0.76 to 1.61) | 0.59 | 1.67 (1.33 to 2.09) | <0.001 | 1.13 (0.87 to 1.46) | 0.37 |
Hospitalisation for New or Worsening HF | 4.70 (3.10 to 7.12) | <0.001 | 2.25 (1.38 to 3.69) | 0.001 | 4.11 (3.04 to 5.54) | <0.001 | 1.81 (1.26 to 2.58) | 0.001 |
CV death or MI | 2.04 (1.53 to 2.71) | <0.001 | 1.35 (0.97 to 1.88) | 0.072 | 2.17 (1.80 to 2.62) | <0.001 | 1.37 (1.10 to 1.70) | 0.005 |
CV death or hospitalisation for new or worsening HF | 4.38 (3.07 to 6.25) | <0.001 | 2.14 (1.40 to 3.25) | <0.001 | 3.55 (2.83 to 4.47) | <0.001 | 1.69 (1.28 to 2.22) | <0.001 |
HR associated with 1 SD increase in logarithmically transformed osteoprotegerin levels at baseline.
Adjusted for Thrombolysis in Myocardial Infarction risk score covariates (including cardiac marker), history of congestive heart failure, creatinine clearance <60 ml/min, gender, body mass index (continuous), B type natriuretic peptide (log transformed) and C reactive protein (log transformed).
CV, cardiovascular; HF, heart failure; MI, myocardial infarction.