Table 2

Cardiovascular disease (CVD) risk classification comparing the ADVANCE CVD prediction model with an extended model which added estimated glomerular filtration rate

Extended model categoriesADVANCE model risk categories for major CVD
<2.4%2.4% to <8%≥8%Total
Participants with an event
 2.4% to <8%02012203
Participants without an event
 2.4% to <8%374276324345
  • To compute the net reclassification improvement, participants were a priori divided into three risk categories: 0% to <2.4%, 2.4% to <8% and ≥8% 4-year predicted probability of major CVD, which extrapolated to predicted 10-year risk groups of <5%, 5–20% and ≥20%, respectively.