Table 2

Overview of the diagnostic accuracy of several combinations of tissue criteria

ValidationSensSpecAccPPVNPV
T2 + LGE
Abdel-Aty et al, 2005Clinical40%100%69%100%61%
Gutberlet et al, 2008Histology17%91%48%73%44%
Pooled data (n=130)25%95%56%86%50%
T2 and/or LGE
Abdel-Aty et al, 2005Clinical88%74%81%100%85%
Gutberlet et al, 2008Histology50%57%52%80%25%
Pooled data (n=130)60%66%62%79%43%
Any one of three
Abdel-Aty et al, 2005Clinical100%48%75%68%100%
Gutberlet et al, 2008Histology81%49%67%68%65%
Pooled data (n=130)88%48%70%68%76%
Any two of three
Abdel-Aty et al, 2005Clinical76%96%85%95%79%
Gutberlet et al, 2008Histology63%89%73%88%63%
Pooled data (n=130)67%91%78%91%69%
  • Table modified from Hundley et al.77

  • Acc, accuracy; LGE, late gadolinium enhancement; NPV, negative predictive value; PPV, positive predictive value; Sens, sensitivity; Spec, specificity.