Validation | Sens | Spec | Acc | PPV | NPV | |
T2 + LGE | ||||||
Abdel-Aty et al, 2005 | Clinical | 40% | 100% | 69% | 100% | 61% |
Gutberlet et al, 2008 | Histology | 17% | 91% | 48% | 73% | 44% |
Pooled data (n=130) | 25% | 95% | 56% | 86% | 50% | |
T2 and/or LGE | ||||||
Abdel-Aty et al, 2005 | Clinical | 88% | 74% | 81% | 100% | 85% |
Gutberlet et al, 2008 | Histology | 50% | 57% | 52% | 80% | 25% |
Pooled data (n=130) | 60% | 66% | 62% | 79% | 43% | |
Any one of three | ||||||
Abdel-Aty et al, 2005 | Clinical | 100% | 48% | 75% | 68% | 100% |
Gutberlet et al, 2008 | Histology | 81% | 49% | 67% | 68% | 65% |
Pooled data (n=130) | 88% | 48% | 70% | 68% | 76% | |
Any two of three | ||||||
Abdel-Aty et al, 2005 | Clinical | 76% | 96% | 85% | 95% | 79% |
Gutberlet et al, 2008 | Histology | 63% | 89% | 73% | 88% | 63% |
Pooled data (n=130) | 67% | 91% | 78% | 91% | 69% |
Table modified from Hundley et al.77
Acc, accuracy; LGE, late gadolinium enhancement; NPV, negative predictive value; PPV, positive predictive value; Sens, sensitivity; Spec, specificity.