Table 1

Baseline characteristics of post-ACS patients based on tertiles of 7-week high sensitivity (hs) troponin T levels

Clinical variablesTertile 1Tertile 2Tertile 3p Value for trend
No of patients104116106
hs Troponin T range (ng/l)<77–1515–2070
Age (SD)58 (11)65 (11)69 (10)<0.001
Male sex (%)6373680.303
BMI (SD)29 (5)26 (4)27 (6)0.002
Medical history (%)
 History of hypertension343761<0.001
 Type II diabetes98170.059
 Hypercholesterolaemia2621110.014
 Smoking history6371580.163
 Previous MI1114250.026
Medication (%)
 Aspirin9289930.612
 Clopidogrel6355530.363
 Statin9496970.585
 β-Blocker8386800.470
 ACE inhibitor6073680.102
Index diagnosis/treatment administered
 Non-ST elevation ACS (%)7959650.008
 Revascularisation (CABG/PCI) (%)3630350.504
 Admission GRACE score (SD)114 (32)139 (31)152 (36)<0.001
Diagnostic tests
 SBP (SD)125 (15)127 (20)131 (21)0.131
 DBP (SD)73 (9)72 (10)72 (11)0.395
 Haemoglobin (g/dl) (SD)13.5 (1.4)13.0 (1.5)12.3 (1.6)<0.001
 Anaemia (%)*184363<0.001
 Total cholesterol (mmol/l) (SD)3.9 (1.0)3.8 (0.9)3.5 (0.8)0.001
 HDL cholesterol (mmol/l) (SD)1.31 (0.56)1.28 (0.35)1.18 (0.320.080
 eGFR (ml/min) (SD)70 (12)67 (16)57 (17)<0.001
 eGFR <60 (%)193253<0.001
 Log 10 BNP (SD)1.6 (0.5)1.9 (0.4)2.3 (0.5)<0.001
 Log 10 hs troponin (SD)0.6 (0.1)1.0 (0.1)1.4 (0.3)<0.001
Echo findings
 Impaired long axis function113457<0.001
 LVSD (%)41632<0.001
 LVH (%)294268<0.001
  • * Anaemia was defined according to the criteria of WHO, that is, haemoglobin level of <12 g/dl in women and haemoglobin of <13 g/dl in men.

  • Impaired long axis function was defined as atrioventricular plane displacement of <1.0 cm.

  • ACS, acute coronary syndrome; BMI, body mass index; BNP, B-type natriuretic peptide; CABG, coronary artery bypass grafting; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; GRACE, Global Registry of Acute Coronary Events; HDL, high density lipoprotein; LVH, left ventricular hypertrophy; LVSD, left ventricular systolic dysfunction; MI, myocardial infarction; PCI, percutaneous coronary intervention; SBP, systolic blood pressure.