Table 1

Mean features of included studies

Study	Location/year	Design	Setting	Therapeutic class	Patients Number^*	Follow-up (months)
Finkelstein Y et al10	Israel/2002	Double-blind RCT	Multicenter	Colchicine	111	3
COPE study1	Italy/2005	Open-label RCT	Single center	Colchicine	120	18
CORE study2	Italy/2005	Open-label RCT	Single center	Colchicine	84	18
COPPS study11	Italy/2010	Double-blind RCT	Multicenter	Colchicine	360	12
CORP study12	Italy/2011	Double-blind RCT	Multicenter	Colchicine	120	18

↵* Real study population included for results analysis in the original study.
RCT, randomised clinical trial.