Table 2

Characteristics of participants aged 30–84 years in the THIN validation cohort

Women (n=1 116 994)Men (n =1 088 619)
Non-statin user (n=987 941)Statin user (n=129 053)Non-statin user (n=935 690)Statin user (n=152 929)
Median age (IQR)45 (37, 58)66 (58, 74)44 (36, 55)63 (55, 71)
Body mass index
 Mean (SD)26.0 (5.0)28.4 (5.3)26.4 (4.1)28.2 (4.4)
 Not recorded, n (%)193 862 (19.6)12 592 (9.8)285 416 (30.5)13 894 (9.1)
Systolic blood pressure
 Mean (SD)128.3 (20.0)141.4 (19.5)132.9 (17.8)140.1 (18.8)
 Not recorded, n (%)70 288 (7.1)699 (0.5)171 733 (18.4)936 (0.6)
Ethnic group
 White/not recorded961 954 (97.4)125 823 (97.5)911 695 (97.4)149 120 (97.5)
 Indian5486 (0.6)900 (0.7)5307 (0.6)1253 (0.8)
 Pakistani1653 (0.2)344 (0.3)1777 (0.2)430 (0.3)
 Bangladeshi510 (0.1)120 (0.1)714 (0.1)142 (0.1)
 Other Asian3105 (0.3)341 (0.3)2825 (0.3)468 (0.3)
 Black Caribbean2708 (0.3)533 (0.4)2141 (0.2)449 (0.3)
 Black African4751 (0.5)335 (0.3)4215 (0.5)274 (0.2)
 Chinese1305 (0.1)66 (0.1)901 (0.1)84 (0.1)
 Other6469 (0.7)591 (0.5)6115 (0.7)709 (0.5)
Smoking status
 Non-smoker453 677 (45.9)64 131 (49.7)342 215 (36.6)50 967 (33.3)
 Ex-smoker121 165 (12.3)36 553 (28,3)132 114 (14.1)62 876 (41.1)
 Current smoker: light (<10 cigarettes/day)64 274 (6.5)6607 (5.1)56 100 (6.0)8794 (5.8)
 Current smoker: moderate (10–9 cigarettes/day)96 453 (9.8)9573 (7.4)90 358 (9.7)10 913 (7.1)
 Current smoker: heavy (≥20 cigarettes/day)66 424 (6.7)7362 (5.7)96 771 (10.3)11 784 (7.7)
 Current smoker: amount not recorded131 756 (13.3)3890 (3.0)107 447 (11.5)6484 (4.2)
 Smoking status not recorded54 192 (5.5)937 (0.7)110 685 (11.8)1 111 (0.7)
Clinical conditions
 Type 1 diabetes1296 (0.1)1650 (1.3)1649 (0.2)2179 (1.4)
 Type 2 diabetes7952 (0.8)26 097 (20.2)10 388 (1.1)32 753 (21.4)
 Cardiovascular disease15 725 (1.6)31 673 (24.5)18 097 (1.9)45 550 (29.8)
 Congestive cardiac failure5080 (0.5)3922 (3.0)4623 (0.5)4877 (3.2)
 Peripheral vascular disease9777 (1.0)5349 (4.1)6688 (0.7)7318 (4.8)
 Treated hypertension60 812 (6.2)54 340 (42.1)38 742 (4.1)53 214 (34.8)
 Rheumatoid arthritis10 533 (1.1)3322 (2.6)4123 (0.4)1831 (1.2)
 Chronic kidney disease 3b+8249 (0.8)11 420 (8.8)4778 (0.5)7731 (5.1)
 Atrial fibrillation6787 (0.7)5868 (4.5)8357 (0.9)8079 (5.3)
 Hypothyroidism33 741 (3.4)14 293 (11.1)4695 (0.5)3380 (2.2)
Outcomes
 Acute renal failure, n618295725399
 Cataract, n11 570399069553177
 Liver dysfunction, n5706124062881522
 Myopathy, n293202400373