Table 4

Association between the presence of depression (BDI-I ≥10) and TDI E_a velocity: multivariate analysis

Variable	Model 1^*		Model 2^†
Variable	Multivariate (β)	p Value	Multivariate (β)	p Value
Age	−0.489	<0.001	−0.451	<0.001
Sex	−0.007	0.660	0.070	<0.001
Body mass index	−0.308	<0.001	−0.227	<0.001
Heart rate			−0.045	0.005
MAP			−0.260	<0.001
Fasting blood glucose			−0.045	0.016
hsCRP			−0.020	0.189
Antihypertensive medication			−0.062	<0.001
Antidiabetic medication			−0.051	0.006
Depression	−0.051	0.002	−0.045	0.004

↵* Model 1: adjusted for age, sex and body mass index.
↵† Model 2: adjusted for model 1 plus heart rate, MAP, fasting blood glucose, hsCRP, medication for hypertension, medication for diabetes.
BDI-I, Beck depression inventory I; MAP, mean arterial pressure; hsCRP, high-sensitivity C reactive protein; TDI, tissue Doppler imaging.