Table 1

Clinical characteristics of patient cohort

N=42
Baseline clinical characteristics
 Age (years±SD)83±6
 Female gender n (%)25 (59%)
 Weight (kg, mean±SD)70±19
 logistic EuroSCORE (mean±SD)22±11
 Diabetes (%)6 (14%)
 Hypertension (%)32 (76%)
 Carotid artery stenosis >50% (%)9 (21%)
 Peripheral vascular disease (%)3 (7%)
 LV function <30%3 (7%)
 Creatine (umol/l)93.6±31.8
 eGFR (ml/min)61.4±16.2
 Coronary artery disease (>50% one and more vessel) (%)28 (66%)
  Severe coronary artery disease (stenosis >50% in two or more vessels or LM disease)12 (28%)
  Angina (%)8 (19%)
  Previous MI (%)8 (19%)
  Prior coronary angioplasty9 (21%)
  Previous cardiac surgery (%)7 (17%)
 NYHA class III/IV (%)34 (81%)
Baseline echocardiographic characteristics
 Aortic valve area (cm2)0.67±0.19
 Mean pressure gradient (mm Hg)47±19
 Peak pressure gradient (mm Hg)84±29
 Ejection fraction (%)51±13
 Mitral regurgitation ≥moderate (%)3 (7%)
  • LV, left ventricular; MI, myocardial infarction; eGFR, estimated glomerular filtration rate; LM, Left main; NYHA, New York Heart Association.