Changes in haemodynamic parameters
| Baseline | 4–6 h | 2–26 h | p Value | |
| Heart rate (bpm) | 67±2 | 71±2* | 78±2* † | <0.05 |
| SBP (mm Hg) | 108±3 | 135±4* | 132±3* † | <0.05 |
| DBP (mm Hg) | 55±2 | 51±1 | 52±2 | NS |
| MAP (mm Hg) | 73±2 | 79±2* | 79±2* | <0.05 |
| CO‡ (l/min) | 3.7±0.82 | 4.5±1.5* | 4.5±1.3* | <0.05 |
| SVR‡ (dyn·s/cm5) | 1266±63 | 1415±89* | 1342±94* | <0.05 |
| SV‡ (ml) | 59±17 | 62±4 | 61±4 | NS |
| PRSW‡ (J/ml) | 45±3 | 52±4* | 50±3* | <0.05 |
ANOVA followed by Newman–Keuls post hoc test; *p<0.05 vs baseline, †p<0.05 vs 6 h.
↵‡ Invasive data for 38 patients.
CO, cardiac output; DBP, diastolic blood pressure; SBP, systolic blood pressure; SV, Stroke volume; SVR, Systemic vascular resistance; MAP, Mean arterial pressure.