Variables | Study population | Thoracic epidural analgesia | p Value | |
No | Yes | |||
n=135 | n=61 | n=74 | ||
30-day/in-hospital outcomes | ||||
Orotracheal reintubation | 16 (11.9) | 14 (22.9) | 2 (2.7) | <0.001 |
Tracheostomy | 6 (4.4) | 6 (9.8) | 0 | 0.007 |
Pneumonia | 11 (8.1) | 9 (14.8) | 2 (2.7) | 0.022 |
Respiratory complications* | 22 (16.3) | 20 (32.8) | 2 (2.7) | <0.001 |
Sepsis | 12 (8.9) | 10 (16.4) | 2 (2.7) | 0.006 |
Haemodialysis | 3 (2.2) | 1 (1.6) | 2 (2.7) | 0.677 |
Stroke | 7 (5.2) | 3 (4.9) | 4 (5.4) | 1.00 |
Myocardial infarction | 2 (1.5) | 2 (3.3) | 0 | 0.202 |
Peak CK-MB (ug/l) | 22.0 (16.1–32.0) | 26.5 (19.1–37.6) | 19.8 (15.0–30.0) | 0.002 |
Peak cardiac troponin T (ug/l) | 0.74 (0.51–1.04) | 0.80 (0.52–1.34) | 0.73 (0.47–0.93) | 0.013 |
New-onset atrial fibrillation | 38 (28.1) | 28 (45.9) | 10 (13.5) | <0.001 |
Major bleeding | 23 (17.0) | 13 (21.3) | 10 (13.5) | 0.253 |
Hospital length (days, IQR) | 8 (7–13) | 10 (7–16) | 8 (6–10) | 0.015 |
30-day death | 14 (10.3) | 12 (19.7) | 2 (2.7) | 0.002 |
In-hospital death | 16 (11.9) | 14 (22.9) | 2 (2.7) | <0.001 |
30 day/in-hospital death | 16 (11.9) | 14 (22.9) | 2 (2.7) | <0.001 |
Late (>30-day/in-hospital to 1-year) outcomes | ||||
Stroke | 1 (0.7) | 0 | 1 (1.4) | 1.00 |
Myocardial infarction | 1 (0.7) | 1 (1.6) | 0 | 0.444 |
Death | 11 (8.1) | 5 (8.2) | 6 (8.1) | 0.750 |
Late (1-year) cumulative outcomes | ||||
Stroke | 8 (5.9) | 3 (4.9) | 5 (6.8) | 0.729 |
Myocardial infarction | 3 (2.2) | 3 (4.9) | 0 | 0.089 |
Death | 27 (20.0) | 19 (31.1) | 8 (10.8) | 0.005 |
Values are mean±SD, n (%) or median (IQR).
↵* Pneumonia or respiratory failure leading to reintubation and/or tracheostomy.
CK-MB: Creatine kinase-MB.