Table 4

Mini-GRACE and adjusted mini-GRACE model calibration and discrimination by acute myocardial infarction type and subgroup

AMI subgroupModelHLT χ2, p valueBrier scoreC statistic (95% CI)Pseudo R2 (%)
 Diabetes mellitusMini-GRACE752.2, p<0.050.120.769 (0.762 to 0.777)17.0
Adjusted mini-GRACE409.9, p<0.050.120.789 (0.782 to 0.796)19.1
 Chronic heart failureMini-GRACE844.4, p<0.050.200.710 (0.698 to 0.722)11.7
Adjusted mini-GRACE351.3, p<0.050.190.723 (0.711 to 0.734)13.2
 Chronic renal failureMini-GRACE1051.5, p<0.050.200.710 (0.697 to 0.723)11.3
Adjusted mini-GRACE252.3, p<0.050.190.719 (0.706 to 0.731)12.5
 Previous revascularisation*Mini-GRACE226.6, p<0.050.090.765 (0.754 to 0.776)14.8
Adjusted mini-GRACE269.8, p<0.050.080.793 (0.782 to 0.803)17.9
 Female sexMini-GRACE454.2, p=0.410.120.790 (0.785 to 0.796)19.4
Adjusted mini-GRACE512.7, p<0.050.120.811 (0.806 to 0.816)22.1
 Age ≥85 yearsMini-GRACE262.2, p<0.050.200.690 (0.682 to 0.698)10.1
Adjusted mini-GRACE243.3, p<0.050.190.717 (0.709 to 0.724)12.3
STEMI subgroup
 Diabetes mellitusMini-GRACE219.3, p<0.050.110.817 (0.804 to 0.831)24.1
Adjusted mini-GRACE139.4, p<0.050.110.832 (0.819 to 0.845)25.8
 Chronic heart failureMini-GRACE229.2, p<0.050.220.774 (0.748 to 0.800)19.0
Adjusted mini-GRACE122.6, p<0.050.200.772 (0.746 to 0.797)19.5
 Chronic renal failureMini-GRACE242.4, p<0.050.200.753 (0.726 to 0.781)16.2
Adjusted mini-GRACE48.9, p<0.050.190.761 (0.734 to 0.787)18.0
 Previous revascularisation*Mini-GRACE107.7, p<0.050.080.768 (0.744 to 0.792)15.6
Adjusted mini-GRACE127.8, p<0.050.080.788 (0.764 to 0.811)17.6
 Female sexMini-GRACE168.1, p=0.120.110.827 (0.819 to 0.835)25.0
Adjusted mini-GRACE241.7, p<0.050.110.844 (0.836 to 0.852)27.7
 Age ≥85 yearsMini-GRACE63.5, p<0.050.200.735 (0.720 to 0.749)14.2
Adjusted mini-GRACE55.3, p=0.140.190.756 (0.742 to 0.770)16.7
NSTEMI subgroup
 Diabetes mellitusMini-GRACE421.8, p<0.050.130.753 (0.744 to 0.762)14.8
Adjusted mini-GRACE269.5, p<0.050.120.774 (0.766 to 0.783)17.0
 Chronic heart failureMini-GRACE631.9, p<0.050.200.701 (0.688 to 0.714)10.4
Adjusted mini-GRACE269.5, p<0.050.190.716 (0.703 to 0.729)12.1
 Chronic renal failureMini-GRACE691.2, p<0.050.200.702 (0.688 to 0.717)10.4
Adjusted mini-GRACE190.5, p<0.050.190.710 (0.696 to 0.724)11.4
 Previous revascularisation*Mini-GRACE160.4, p=0.060.090.767 (0.754 to 0.779)15.0
Adjusted mini-GRACE160.9, p=0.050.080.796 (0.784 to 0.808)18.3
 Female sexMini-GRACE325.5, p=0.170.120.773 (0.766 to 0.779)16.9
Adjusted mini-GRACE354.8, p<0.050.120.795 (0.789 to 0.802)19.6
 Age ≥85 yearsMini-GRACE178.8, p<0.050.200.676 (0.667 to 0.685)8.6
Adjusted mini-GRACE197.8, p<0.050.190.704 (0.695 to 0.712)10.7
  • Pseudo R2 refers to McFadden's pseudo R2.

  • *Percutaneous coronary intervention and/or coronary artery bypass grafting.

  • AMI, acute myocardial infarction; GRACE, Global Registry of Acute Coronary Events; HLT, Hosmer–Lemeshow goodness of fit test; NSTEMI, non-ST elevation myocardial infarction; STEMI, ST elevation myocardial infarction.