Quartile (Qn) of covariate | ||||||
---|---|---|---|---|---|---|
Covariate | Q1 | Q2 | Q3 | Q4 | Ratio | p Value |
Demographic data | ||||||
Age (59; 64; 68) years | 4.40 | 10.0 | 5.75 | 13.3 | 1.32 | 0.002 |
BMI (20; 24; 27) kg/m2 | 9.68 | 6.56 | 10.61 | 5.45 | 0.88 | 0.136 |
Pack-years | 5.21 | 6.64 | 10.40 | 9.55 | 1.25 | 0.011 |
Clinical data | ||||||
Heart rate (67; 81; 96) 1/min | 3.80 | 4.89 | 8.69 | 19.79 | 1.75 | <0.001 |
Systolic BP (123; 136; 150) mm Hg | 8.47 | 9.03 | 10.07 | 5.67 | 0.87 | 0.123 |
CAT score (16; 20; 27) | 3.19 | 4.66 | 10.84 | 15.46 | 1.74 | <0.001 |
Spirometry | ||||||
FVC (1.78; 2.31; 3.07) l | 11.0 | 8.03 | 8.28 | 4.66 | 0.77 | 0.005 |
FEV1 (0.66; 0.89; 1.38) l | 11.0 | 9.80 | 6.23 | 4.40 | 0.76 | 0.003 |
FEV1 to FVC (0.34; 0.42; 0.51) | 8.94 | 9.59 | 6.91 | 5.91 | 0.85 | 0.085 |
Arterial blood gases and pH | ||||||
(8.1; 9.0; 9.8) kPa | 12.0 | 7.8 | 7.2 | 4.8 | 0.75 | 0.003 |
(5.0; 5.6; 6.3) kPa | 5.7 | 6.6 | 6.8 | 18.6 | 1.39 | 0.001 |
pH (7.39; 7.42; 7.44) | 10.2 | 6.3 | 6.3 | 8.7 | 0.94 | 0.489 |
Laboratory data | ||||||
Haemoglobin (13.3; 14.4; 15.2) g/dl | 11.3 | 8.53 | 4.16 | 8.71 | 0.85 | 0.094 |
Leucocytes (6.9; 8.1; 11.1) 10−9/l | 4.39 | 3.45 | 8.13 | 23.01 | 1.82 | <0.001 |
CRP (1.9; 4.5;23.5) mg/l | 3.75 | 3.98 | 4.93 | 5.40 | 0.139 | 0.164 |
Creatinine (57; 71; 85) µmol/l | 9.08 | 6.39 | 6.09 | 10.28 | 1.04 | 0.680 |
Quartile limits in parentheses.
Ratio: (hs-cTnT)Qn/(hs-cTnT)Qn−1.
BMI, body mass index; BP, blood pressure; CAT score, COPD Assessment Test; COPD, chronic obstructive pulmonary disease; CRP, C reactive protein; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.