Table 1

Characteristics of the 595 patients in the cross-sectional study

Overall (n=595)Non-significant (n=177)AS dominant (n=267)AR dominant (n=117)ASR dominant (n=34)p Value
Age (years)53.4±14.348.8±14.360.2±10.744.6±13.954.1±15.4<0.001
Male gender (%)65.565.057.382.176.5<0.001
Weight (kg)64.0±10.764.6±11.262.3±10.767.8±9.763.1±9.1<0.001
Height (cm)163±9165±8161±9167±7165±6<0.001
Body surface area (m2)1.70±0.171.72±0.181.66±0.171.77±0.151.70±0.15<0.001
Body mass index (kg/m2)23.9±3.023.8±3.124.0±3.024.1±3.023.2±2.80.472
Hypertension (%)60.755.960.367.564.70.242
Diabetes mellitus (%)11.611.915.82.68.80.001
Smoking (%)36.733.538.337.039.40.784
Cholesterol>240 mg/dl (%)17.214.221.213.811.80.155
Coronary artery disease (%)13.411.019.23.712.1<0.001
Use of β-blocker (%)9.911.811.34.48.80.128
Systolic BP (mm  Hg)130±19129±15127±17139±25129±18<0.001
Diastolic BP (mm  Hg)78±1281±1180±1072±1474±9<0.001
LVESV (ml)49±4037±1735±2393±5773±41<0.001
LVEDV (ml)118±7295±3189±38205±96161±84<0.001
LV ejection fraction (%)60±862±762±857±856±11<0.001
LV mass index (g/m2)159.5±61.9114.0±30.5162.5±49.4193.0±77.0220.4±70.4<0.001
Aortic diameter (mm)*
 Sinus portion34.0 (31.0–38.0)34.0 (31.0–38.0)33.0 (30.0–37.0)37.5 (33.0–41.3)34.0 (31.5–39.1)<0.001
 Tubular portion40.0 (35.0–45.0)37.0 (32.0–43.0)42.0 (38.0–47.0)38.0 (33.0–43.5)43.0 (39.0–47.0)<0.001
Aortic diameter (mm/m2)*
 Sinus portion20.3 (18.1–22.6)19.7 (17.6–22.0)20.1 (18.0–22.5)21.2 (18.9–24.1)20.9 (18.2–22.4)0.003
 Tubular portion23.6 (20.6–27.4)21.7 (18.6–24.9)25.2 (22.5–29.0)21.0 (18.9–24.6)25.5 (22.9–28.3)<0.001
  • *Data are presented as median with IQR.

  • AR, aortic regurgitation; AS, aortic stenosis; BP, blood pressure; LV, left ventricular; LVEDV, LV end diastolic volume; LVESV, LV end systolic volume.