Table 2

Cox regression analysis of predicting significant TR after successful PMV in the entire population

	Univariate analysis		Multivariate analysis
	HR (95% CI)	p Value	HR (95% CI)^*	p Value^*	HR (95% CI)^†	p Value^†
Age	1.075 (1.046 to 1.105)	<0.001	1.032 (0.981 to 1.086)	0.225	1.020 (0.974 to 1.069)	0.396
Female	1.194 (0.584 to 2.439)	0.627
Pre-PMV atrial fibrillation	6.239 (3.394 to 11.468)	<0.001	3.049 (1.169 to 7.949)	0.023	4.601 (1.689 to 12.537)	0.003
Pre-PMV MVA	0.524 (0.217 to 1.264)	0.150
Pre-PMV PASP	0.995 (0.981 to 1.009)	0.481
Pre-PMV LA volume	1.010 (1.006 to 1.013)	<0.001	0.998 (0.988 to 1.009)	0.780	0.998 (0.987 to 1.009)	0.737
Pre-PMV mean LA pressure	0.971 (0.943 to 1.011)	0.976
Echo score	1.226 (1.060 to 1.418)	0.006	1.098 (0.906 to 1.331)	0.340	1.126 (0.919 to 1.380)	0.253
Pre-PMV TR grade ≥2	3.022 (1.762 to 5.181)	<0.001	3.016 (1.303 to 6.982)	0.010
Pre-PMV TR grade ≥3	4.195 (2.089 to 8.426)	<0.001			4.384 (1.560 to 12.322)	0.005
Pre-PMV LVEF	0.961 (0.930 to 0.993)	0.017	0.973 (0.934 to 1.014)	0.198	0.979 (0.938 to 1.021)	0.316
Post-PMV MVA	0.615 (0.416 to 0.910)	0.015	1.105 (0.617 to 1.980)	0.736	1.266 (0.730 to 2.195)	0.401
Post-PMV PASP	1.034 (1.010 to 1.058)	0.006	1.038 (0.995 to 1.083)	0.081	1.034 (0.996 to 1.073)	0.077
Post-PMV LA volume	1.010 (1.006 to 1.014)	<0.001	1.004 (0.994 to 1.014)	0.420	1.004 (0.993 to 1.014)	0.494
Post-PMV mean LA pressure	1.096 (1.039 to 1.156)	0.001	1.046 (0.945 to 1.157)	0.386	1.027 (0.923 to 1.143)	0.621

↵* HR and p value were calculated with pre-PMV TR grade ≥2 as a covariate.
↵† HR and p value were calculated with pre-PMV TR grade ≥3 as a covariate.
LA, left atrium; LVEF, left ventricular ejection fraction; MVA, mitral valve area; PASP, pulmonary artery systolic pressure; PMV, percutaneous mitral valvuloplasty; TR, tricuspid regurgitation.